CHEMGRID MOLECULE CARD
8-Sulfamoyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
8-Sulfamoyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
2374-0101
Explore activity & SONAR![Chemical structure of 8-Sulfamoyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid](/structure-thumbnails/ChemDiv-Kinase/23/2374-0101.svg?v=2026-09-22T13%3A54%3A31%2B00%3A00)
Identity and chemistry
- ChemGrid identifier
- 2374-0101
- Molecular formula
- C13H14N2O4S
- InChIKey
- ILJBOVQNAKDIKN-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
NS(=O)(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=OMatched external records: PubChem 2868734
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| Dusp6 · Dual specificity protein phosphatase 6 | ChEMBL | No stored yeast mapping |
| GAPDH · Glyceraldehyde-3-phosphate dehydrogenase | ChEMBL | TDH3 YGR192C (ortholog_one2many); TDH1 YJL052W (ortholog_one2many); TDH2 YJR009C (ortholog_one2many) |
| HSPA1A · Heat shock 70 kDa protein 1A | ChEMBL | SSE2 YBR169C (ortholog_many2many); SSE1 YPL106C (ortholog_many2many) |
| HSPA8 · Heat shock cognate 71 kDa protein | ChEMBL | SSE2 YBR169C (ortholog_many2many); SSE1 YPL106C (ortholog_many2many) |
| PTPN7 · Tyrosine-protein phosphatase non-receptor type 7 | ChEMBL | No stored yeast mapping |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 8-Sulfamoyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.