CHEMGRID MOLECULE CARD
5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol
5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
1075-0001
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- 1075-0001
- Molecular formula
- C10H13N5O3
- InChIKey
- OLXZPDWKRNYJJZ-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
Nc1ncnc2n(cnc12)C1CC(O)C(CO)O1Matched external records: PubChem 636
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| ffp · 4'-phosphopantetheinyl transferase ffp | ChEMBL | No stored yeast mapping |
| LMNA · Prelamin-A/C | ChEMBL | No stored yeast mapping |
| Luciferin 4-monooxygenase | ChEMBL analogue | No stored yeast mapping |
| AVPR1B · Vasopressin V1b receptor | ChEMBL analogue | No stored yeast mapping |
| HIF1A · Hypoxia-inducible factor 1-alpha | ChEMBL analogue | No stored yeast mapping |
| HTT · Huntingtin | ChEMBL analogue | No stored yeast mapping |
| RXFP1 · Relaxin receptor 1 | ChEMBL analogue | No stored yeast mapping |
| RXFP2 · Relaxin receptor 2 | ChEMBL analogue | No stored yeast mapping |
| SLC5A7 · High affinity choline transporter 1 | ChEMBL analogue | DUR3 YHL016C (ortholog_one2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete 5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.