CHEMGRID MOLECULE CARD
Carboxin
Carboxin in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.
000A-0955
Explore activity & SONAR
Identity and chemistry
- ChemGrid identifier
- 000A-0955
- Molecular formula
- C12H13NO2S
- InChIKey
- GYSSRZJIHXQEHQ-UHFFFAOYSA-N
- Libraries
- ChemDiv-Kinase
Stored SMILES
CC1OCCSC=1C(=O)Nc1ccccc1Matched external records: PubChem 21307
Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.
Measured chemical–genetic activity
3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).
Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.
Recorded target evidence and yeast matches
Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.
| Target | Source | Yeast ORF / orthologue |
|---|---|---|
| CBX1 · Chromobox protein homolog 1 | ChEMBL | No stored yeast mapping |
| EHMT2 · Histone-lysine N-methyltransferase EHMT2 | ChEMBL | SET2 YJL168C (ortholog_many2many) |
| HSD17B10 · 3-hydroxyacyl-CoA dehydrogenase type-2 | ChEMBL | No stored yeast mapping |
| MAPK1 · Mitogen-activated protein kinase 1 | ChEMBL | SLT2 YHR030C (ortholog_many2many); YKL161C (ortholog_many2many) |
| NFE2L2 · Nuclear factor erythroid 2-related factor 2 | ChEMBL | No stored yeast mapping |
| PPARD · Peroxisome proliferator-activated receptor delta | ChEMBL | No stored yeast mapping |
| PTH1R · Parathyroid hormone/parathyroid hormone-related peptide receptor | ChEMBL | No stored yeast mapping |
| RAPGEF3 · Rap guanine nucleotide exchange factor 3 | ChEMBL | LTE1 YAL024C (ortholog_many2many); CDC25 YLR310C (ortholog_many2many) |
Structural activity predictions and SONAR
Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.
SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.
Open the complete Carboxin research profile →Sources and provenance
Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.
Card snapshot: 2026-11-02. Linked interactive views may contain newer data.