ChemGrid

CHEMGRID MOLECULE CARD

N4,N4-Dimethyl-6-phenylpyrimidine-2,4-diamine

N4,N4-Dimethyl-6-phenylpyrimidine-2,4-diamine in ChemGrid: 3 screened assays, 0 with significant responses. Explore chemical identifiers, strain activity and target evidence.

000A-0319

Explore activity & SONAR
Chemical structure of N4,N4-Dimethyl-6-phenylpyrimidine-2,4-diamine
Stored molecular structure
3Screened assays
0Significant assay responses
3Source-labelled target records

Identity and chemistry

ChemGrid identifier
000A-0319
Molecular formula
C12H14N4
InChIKey
JZARMCYNEGDPGB-UHFFFAOYSA-N
Libraries
ChemDiv-Kinase
Stored SMILESCN(C)c1cc(nc(N)n1)c1ccccc1

Matched external records: PubChem 677167

Chemical identifiers and library names are reproduced from ChemGrid records. Missing values are omitted.

Measured chemical–genetic activity

3 measurements across 3 distinct library–species–strain assays; 0 assays have at least one significant response (|Z| ≥ 4, p ≤ 0.001, excluding flagged outliers).

Responses are indirect screening phenotypes. They do not establish that a strain gene is a direct molecular target. Strains and timepoints are retained as recorded; these counts are not counts of unique ORFs.

Recorded target evidence and yeast matches

Source annotations are shown separately from SONAR hypotheses. Evidence type and identity matching can vary; consult the linked source and interactive evidence panel.

TargetSourceYeast ORF / orthologue
CBX1 · Chromobox protein homolog 1ChEMBLNo stored yeast mapping
GMNN · GemininChEMBLNo stored yeast mapping
TDP1 · Tyrosyl-DNA phosphodiesterase 1ChEMBLTDP1 YBR223C (ortholog_one2one)

Structural activity predictions and SONAR

Stored structural activity predictions are available in the interactive profile, with assay-specific cutoffs and applicability-domain assessments.

SONAR ranks candidate targets through genetic and physical interaction evidence. Structural SONAR uses predicted strain responses; measured SONAR uses experimental responses. These are experimental hypotheses, not confirmed binding targets. Outside-domain predictions are treated as unknown.

Open the complete N4,N4-Dimethyl-6-phenylpyrimidine-2,4-diamine research profile →

Sources and provenance

Screening measurements: ChemGrid chemical-genetic datasets. Wildenhain et al., Cell Systems (2015). Target annotations: sources named in the evidence table. Structure and library metadata: stored ChemGrid catalogue records.

Card snapshot: 2026-11-02. Linked interactive views may contain newer data.