Description: One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks
Function: 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme
