Description: Inositol phosphosphingolipid phospholipase C, hydrolyzes inositolphosphosphingolipids, activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol, mediates Na+ and Li+ halotolerance, contains a P loop-like domain
Function: ISC1 encodes phospholipase C type enzyme which hydrolyzes inositolphosphosphingolipids (IPC, MIPC, M(IP)2C) as well as sphingomyelin.