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SONAR Targetspace for COLCHICEINEZ-score WebGraph NB WebGraph
Targetspace hs 285 127
Targetspace hs pval0.0503144654088050.31842105263158
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:33
Sym Orf Description Function No All Z_score hyperg
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 11 111 -4.2054 0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 145 -15.8415 NAN
VPS9 YML097C A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar prote...   10 88   0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 8 81 -15.3397 0
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 8 128   0
ELM1 YKL048C Serine/threonine protein kinase that regulates cellular morphogenesis, septin be... protein kinase 7 68   0
COG5 YNL051W Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   7 89   0
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 7 126   NAN
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 7 108 0.2319 0
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, ... mannosyltransferase complex component 7 31   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   7 62   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   7 64   0.0252
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 7 64 -8.8337 0.0013
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... function unknown 6 110   0.1003
SAC6 YDR129C Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in ... actin filament bundling protein|fimbrin homolog 6 53   0.1699
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 6 62   0.0168
HRD3 YLR207W Resident protein of the ER membrane that plays a central role in ER-associated p...   6 48   0
USA1 YML029W Protein that interacts in the two-hybrid system with the U1 snRNP-specific prote... pre-mRNA splicing factor (putative) 6 39   0
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to ...   6 19   0.0386
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   6 93 -15.3594 0.0016
ILM1 YJR118C Protein of unknown function; may be involved in mitochondrial DNA maintenance; r...   5 108   0.1016
CUP5 YEL027W Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohex... 17 kDa|VO sector subunit|dicyclohexylcarbodiimide binding subunit|proteolipid|vacuolar ATP synthase proteolipid C|vacuolar ATPase V0 domain subunit c (dicyclohexylcarbodiimide binding subunit) (17 kDa) 5 14   0.0343
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   5 54   0
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation via three independen... MAP kinase 5 81   0.0329
RAD17 YOR368W Checkpoint protein, involved in the activation of the DNA damage and meiotic pac... 3--5-exonuclease (putative) 5 85   0.0012
KEX2 YNL238W Subtilisin-like protease (proprotein convertase), a calcium-dependent serine pro... Ca2+-dependent serine protease 5 86   0.1133
BUD14 YAR014C Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cort...   5 29   0.0001
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   5 140   0
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domain...   5 41   0.1099
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that gener... 1-phosphatidylinositol-3-phosphate 5-kinase 5 37   0.016
SAM37 YMR060C Component of the mitochondrial outer membrane sorting and assembly machinery (SA... mitochondrial SAM complex constituent 5 28   0.1603
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 4 61   0.0258
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 4 28   0

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