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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 6 67 -1.2210 0
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 6 56   0.0005
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   5 47   0.1819
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   5 30   0.1876
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   5 21   0.1094
GSG1 YDR108W Subunit of TRAPP (transport protein particle), a multi-subunit complex involved ...   5 97   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   5 32   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   5 48   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   5 16   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   4 25   0.1995
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 4 15   0
PEP8 YJL053W Vacuolar protein sorting protein that forms part of the multimeric membrane-asso... vacuolar protein similar to mouse gene H<beta>58 4 27   0
  ETG9627     4 5   0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   4 42 -3.4353 0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   4 41   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 4 20   0.0043
VMA7 YGR020C Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPa... vacuolar ATPase V1 domain subunit F (14 kDa) 3 14   0.0737
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 3 9   0
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane, responsible for the major...   3 7   0.232
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in t... phosphatidyl-ethanolamine N-methyltransferase 3 33   0.0571
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   3 20   0.034
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 3 19   0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   3 41   0
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 3 33   0.0895
  YIL039W     3 65   0
VMA22 YHR060W Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) fun...   3 17   0.0874
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 23   0
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 3 10   0
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   3 56   0
VMA10 YHR039C-A Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar ... vacuolar ATPase V1 domain subunit G (13 kDa) 3 5   0
MAK10 YEL053C Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required...   3 17   0.0376
SBH1 YER087C-B Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involv... Sbh2p homolog 3 11   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   3 73   0.0019
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required...   3 5   0
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 3 21   0.0221
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 3 15   0
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 3 33   0.2144
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 3 65   0.0069

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