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SONAR Targetspace for MADECASSIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 143 0
Targetspace hs pval0.621359223300971
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 9 62   0.135
HKR1 YDR420W Serine/threonine rich cell surface protein that contains an EF hand motif; invol... contains EF hand motif|type I transmembrane protein 8 25   0
LAS21 YJL062W Integral plasma membrane protein involved in the synthesis of the glycosylphosph... major facilitator superfamily (putative)|membrane protein (putative) 7 74   0
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member involved in genome ... high mobility group (HMG) family 6 60   0.0433
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
SBE2 YDR351W Protein involved in the transport of cell wall components from the Golgi to the ...   5 7   0.018
POG1 YIL122W Putative transcriptional activator that promotes recovery from pheromone induced... transcription factor (putative) 5 7   0
STE20 YHL007C Signal transducing kinase of the PAK (p21-activated kinase) family, involved in ...   5 60   0.0004
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   4 16   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   4 30   0.1709
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by bot... glycerol-3-phosphate dehydrogenase 4 10   0
NPL6 YMR091C Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p,...   4 81   0.1287
SHO1 YER118C Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP... transmembrane osmosensor 3 17   0
SLN1 YIL147C Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane p... histidine kinase osmosensor that regulates an osmosensing MAP kinase cascade|similar to bacterial two-component regulators 3 11   0.0018
STE7 YDL159W Signal transducing MAP kinase kinase involved in pheromone response, where it ph... MAP kinase kinase (MEK) 3 17   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 3 13   0
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity and respon...   3 7   0
MTL1 YGR023W Protein with both structural and functional similarity to Mid2p, which is a plas... acts in concert with Mid2p to transduce cell wall stress signals 3 11   0
SEM1 YDR363W-A Component of the lid subcomplex of the regulatory subunit of the 26S proteasome;...   3 43   0
SSK2 YNR031C MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; intera... MAP kinase kinase kinase|activator of Pbs2p 3 22   0.0114
SSK1 YLR006C Cytoplasmic response regulator, part of a two-component signal transducer that m... two-component signal transducer that with Sln1p regulates osmosensing MAP kinase cascade(suppressor of sensor kinase) 3 23   0
HST1 YOL068C NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p...   3 25   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   3 15   0
TEC1 YBR083W Transcription factor required for full Ty1 epxression, Ty1-mediated gene activat... TEA/ATTS DNA-binding domain family transcription factor 3 17   0.225
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 3 38   0
ARR3 YPR201W Arsenite transporter of the plasma membrane, required for resistance to arsenic ...   3 7   0
MST1 YKL194C Mitochondrial threonyl-tRNA synthetase   3 4   0.0001
  YPR045C     3 14   0.0008
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   3 10   0
EMP24 YGL200C Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicl... type I transmembrane protein 3 25   0
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turno... Pdr16p homolog|Sec14p homolog 3 11   0.0019
YTA12 YMR089C Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that m... ATPase|CDC48/PAS1/SEC18 (AAA) family 3 16   0.0077
RSC9 YML127W One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; DN...   3 13   0.0021
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   3 48   0
IRE1 YHR079C Serine-threonine kinase and endoribonuclease; transmembrane protein that initiat... endoribonuclease|serine-threonine kinase|transmembrane protein 3 49 -1.1366 0.0898
YPD1 YDL235C Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor ... two-component phosphorelay intermediate 3 5   0
STE5 YDR103W Scaffold protein that, in response to pheromone, shuttles from the nucleus to th...   3 26   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 3 59   0.0002

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