Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 15 25   0.0115
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 14 19   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 12 104   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   11 48   0.0001
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 10 62   0.1415
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   9 72   0.1027
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 9 145   NAN
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 8 67 -5.8010 0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   8 71   0.1083
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 8 111   0
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   7 100   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   7 54   0
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   7 24   0.0002
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 56   0.0014
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   6 32   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   6 22   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   6 26   0.0311
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   6 42 -6.8158 0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   6 21   0.0534
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 5 46   0
VAM7 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-... heptad repeat motif|hydrophilic protein 5 17   0.1676
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 57   0
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes th... dolichol phosphate mannose synthase 5 8   0.0002
SUM1 YDR310C Transcriptional repressor required for mitotic repression of middle sporulation-...   5 139   0.1862
SUR1 YPL057C Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synth... integral membrane protein 5 40   0.0055
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   5 23   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 5 20   0.0005
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   5 56   0
YPK2 YMR104C Protein kinase with similarityto serine/threonine protein kinase Ypk1p; function... protein kinase 5 12   0
POG1 YIL122W Putative transcriptional activator that promotes recovery from pheromone induced... transcription factor (putative) 5 7   0
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 5 8   0.1507
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   5 22   0
CDC15 YAR019C Protein kinase of the Mitotic Exit Network that is localized to the spindle pole... protein kinase domain 5 66   0.1399
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   5 44   0
  YKL161C     5 5   0.0912

Service provided by the Mike Tyers Laboratory