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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
RGA1 YOR127W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... rho GTPase activating protein (GAP) 3 17   0.0466
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   2 82   0
RBL2 YOR265W Protein involved in microtubule morphogenesis, required for protection from exce... tubulin folding cofactor A 2 30 -1.9457 0
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant... GTP-binding protein 2 26   0
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   2 47   0
SIT4 YDL047W Type 2A-related serine-threonine phosphatase that functions in the G1/S transiti... similar to catalytic subunit of bovine type 2A protein phosphatase 2 77   0.0018
SSH1 YBR283C Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translatio...   2 88   0
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p in response to alkaline pH...   2 33   0.1512
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 2 36   0.277
PHO80 YOL001W Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK com... Pho80p cyclin 2 145   0.1218
HXK1 YFR053C Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of gl... hexokinase I (PI) (also called hexokinase A) 2 6   0.2553
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 2 6   0.2679
FOB1 YDR110W Nucleolar protein required for DNA replication fork blocking and recombinational... DNA replication fork blocking protein 2 23   0.2812
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane low affinity Fe2+ transport protein 2 7   0.1886
SPT15 YER148W TATA-binding protein, general transcription factor that interacts with other fac... TFIID subunit 2 53   0.0054
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involv... GTP-binding protein|rho subfamily 2 26   0.1895
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 2 46   0
PXL1 YKR090W LIM domain-containing protein that localizes to sites of polarized growth, requi...   2 4   0.1236
ACT1 YFL039C Actin, structural protein involved in cell polarization, endocytosis, and other ... actin 2 77   0.281
GRR1 YJR090C F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p ...   2 42   0.0581
MSB1 YOR188W Protein involved in positive regulation of both 1,3-beta-glucan synthesis and th...   2 11   0.1078
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton o... rho GTPase activating protein (GAP) 2 22   0.2351
PAC1 YOR269W Protein involved in nuclear migration, part of the dynein/dynactin pathway; targ...   2 32   0.0271
GIC1 YHR061C Protein of unknown function involved in initiation of budding and cellular polar...   2 37   0.2833
ERG11 YHR007C Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol ... cytochrome P450 lanosterol 14a-demethylase 2 79   0.001
UPC2 YDR213W Sterol regulatory element binding protein, induces transcription of sterol trans... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 2 24   0
CDC55 YGL190C Non-essential regulatory subunit B of protein phosphatase 2A; has multiple roles... protein phosphatase 2A regulatory subunit B 2 44   0.0626
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA durin... ssDNA endonuclease 2 32   0
TPK3 YKL166C Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant c... cAMP-dependent protein kinase catalytic subunit 2 22   0.0237
MOT1 YPL082C Essential abundant protein involved in regulation of transcription, removes Spt1... helicase (putative) 2 28   0.0025
TOA1 YOR194C TFIIA large subunit; involved in transcriptional activation, acts as antirepress... transcription factor IIA subunit alpha 2 9   0
TOA2 YKL058W TFIIA small subunit; involved in transcriptional activation, acts as antirepress... beta|transcription factor IIA subunit 2 11   0
SET3 YKR029C Defining member of the SET3 histone deacetylase complex which is a meiosis-speci...   2 90   0
MMS2 YGL087C Protein involved in error-free postreplication DNA repair; forms a heteromeric c...   1 42   0.2892
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosi... tRNA:m5C-methyltransferase 1 13   0.2531
SIF2 YBR103W WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which r...   1 61   0
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 1 109 -1.0735 0
ISA2 YPR067W Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, lo...   1 3   0.3572
SIT1 YEL065W Ferrioxamine B transporter, member of the ARN family of transporters that specif... ferrioxamine B permease 1 8   0.3225

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