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SONAR Targetspace for TETRANDRINEZ-score WebGraph NB WebGraph
Targetspace hs 89 93
Targetspace hs pval0.325396825396830.565625
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 2 30   0.1703
ACF2 YLR144C Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; ...   2 18   0
NOT3 YIL038C Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... CCR4 transcriptional complex component 2 31   0.2012
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   2 39   0.069
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 2 9   0.2568
CAF130 YGR134W Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex...   2 23   0.0145
BTT1 YDR252W Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex (alph...   2 11   0
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 2 53   0.0018
VPH2 YKL119C Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, a... 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase 2 8   0
CDC36 YDL165W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 2 34   0.0419
YBP2 YGL060W Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, ...   1 26   0.3652
SLF1 YDR515W RNA binding protein that associates with polysomes; proposed to be involved in r...   1 6   0
  YGL226W     1 3   0
KAP122 YGL016W Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nuc... karyopherin beta family member 1 25   0.083
YRF1-1 YDR545W Helicase encoded by the Y- element of subtelomeric regions, highly expressed in ... Y--helicase protein 1 1 7   0
RTG2 YGL252C Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p...   1 34   0.3246
PMI40 YER003C Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and... mannose-6-phosphate isomerase 1 7   0.1917
EXO70 YJL085W Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec1... exocyst complex component 1 24   0
ESP1 YGR098C Separase with cysteine protease activity (related to caspases) that promotes sis... separase 1 13   0
  YLR243W     1 5   0
VRP1 YLR337C Proline-rich, actin-associated protein involved in cytoskeletal organization and... proline-rich protein verprolin 1 21   0.0007
  YJR115W     1 7   0
ACF4 YJR083C Protein of unknown function, computational analysis of large-scale protein-prote...   1 10   0
HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain with sequence similarity to ...   1 21   0
RRP3 YHR065C Protein involved in rRNA processing; required for maturation of the 35S primary ... weak RNA-dependent ATPase activity which is not specific for rRNA 1 8   0
SLN1 YIL147C Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane p... histidine kinase osmosensor that regulates an osmosensing MAP kinase cascade|similar to bacterial two-component regulators 1 13   0.1917
RPL19B YBL027W Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1... ribosomal protein L19B (YL14) (L23B) (rpl5L) 1 72   0.1992
GFD2 YCL036W Protein of unknown function, identified as a high-copy suppressor of a dbp5 muta...   1 3   0
POP2 YNR052C RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3- ... transcription factor (putative) 1 48 -1.4772 0
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 1 41   0.0009
MPT5 YGL178W Protein that specifically binds to mRNAs encoding chromatin modifiers and spindl...   1 19   0.2517
CAF120 YNL278W Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex...   1 5   0.2264
  YMR181C     1 11   0
  ETG9337     1 12   0
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex, which is involved in regulati...   1 57 -6.2835 0
CAF16 YFL028C Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex... ABC ATPase 1 10   0
PUF3 YLL013C Protein that regulates degradation of specific mRNAs such as COX17, binds almost...   1 31   0
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 1 31   0.3092
  ETG18983     1 4   0
TBS1 YBR150C Probable Zn-finger protein   1 8   0.0405

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