Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:17
Sym Orf Description Function No All Z_score hyperg
XRS2 YDR369C Protein required for DNA repair; component of the Mre11 complex, which is involv... DNA repair protein 2 20   0
RFA2 YNL312W Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... 29% identical to the human p34 subunit of RF-A|replication factor RF-A subunit 2 2 37   0.1092
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of... NADP-dependent isocitrate dehydrogenase 1 16   0.3622
PTC3 YBL056W Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit ma... protein phosphatase type 2C 1 21   0.1537
INH1 YDL181W Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase, inhibitory functi... ATPase inhibitor 1 14   0
RAD50 YNL250W Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-str... Mre11-Rad50-Xrs2 protein complex member involved in joining double-stranded breaks and DNA recombination 1 41 -22.6071 0
END3 YNL084C EH domain-containing protein involved in endocytosis, actin cytoskeletal organiz...   1 27   0.0608
ECM10 YEL030W Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, pl...   1 27   0
REX2 YLR059C RNA exonuclease, required for U4 snRNA maturation; functions redundantly with Rn... RNA exonuclease 1 10   0.002
IES5 YER092W Protein that associates with the INO80 chromatin remodeling complex under low-sa...   1 28   0.2136
RDH54 YBR073W DNA-dependent ATPase, stimulates strand exchange by modifying the topology of do... helicase (putative)|similar to RAD54 1 7   0.3771
DDC1 YPL194W DNA damage checkpoint protein, part of a PCNA-like complex required for DNA dama...   1 17   0
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cycl...   1 11   0.035
ALD5 YER073W Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of ... aldehyde dehydrogenase 1 4   0
RAD9 YDR217C DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S,... cell cycle arrest protein 1 16   0
RIM1 YCR028C-A Single-stranded DNA-binding protein essential for mitochondrial genome maintenan... DNA binding protein 1 31   0
HEX3 YDL013W Ring finger protein involved in the DNA damage response with possible recombinat...   1 57   0

Service provided by the Mike Tyers Laboratory