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SONAR Targetspace for PHYSCIONZ-score WebGraph NB WebGraph
Targetspace hs 209 321
Targetspace hs pval0.0266393442622950.018292682926829
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RFA2 YNL312W Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... 29% identical to the human p34 subunit of RF-A|replication factor RF-A subunit 2 2 37   0.1092
XRS2 YDR369C Protein required for DNA repair; component of the Mre11 complex, which is involv... DNA repair protein 2 20   0
RIM1 YCR028C-A Single-stranded DNA-binding protein essential for mitochondrial genome maintenan... DNA binding protein 2 31   0
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
  YER160C     1 8   0
ROG3 YFR022W Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY...   1 10   0
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation; forms complex... protein with COPI and COPII bindng motifs 1 20   0
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlap... protein disulfide isomerase homolog 1 3   0
NPR2 YEL062W Regulator of nitrogen permeases; transcription is induced in response to proline...   1 18   0.083
  YER138C     1 11   0
PCL10 YGL134W Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein ...   1 25   0
MDS3 YGL197W Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 21   0.0484
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosi... plasma membrane pyridoxine transport protein 1 1   0
PRM5 YIL117C Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced ...   1 4   0
PRM10 YJL108C Pheromone-regulated protein, predicted to have 5 transmembrane segments   1 6   0
  YJR129C     1 4   0.1265
RMD11 YHL023C Protein required for sporulation   1 14   0.0293
  YGR126W     1 13   0.0995
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 1 25   0.2106
  YGR001C     1 8   0
  YGR012W     1 4   0
  YDR134C     1 16   0.1878
  YJR141W     1 12   0
  YBR225W     1 13   0.0293
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   1 17   0.006
IST2 YBR086C Plasma membrane protein that may be involved in osmotolerance, localizes to the ...   1 22   0.1309
QDR3 YBR043C Multidrug transporter required for resistance to quinidine, barban, cisplatin, a...   1 3   0
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosi... tRNA:m5C-methyltransferase 1 32   0.2531
  YBL100W-A     1 1   0
CHS2 YBR038W Chitin synthase II, requires activation from zymogenic form in order to catalyze... chitin synthase 2 1 5   0.3203
PRD1 YCL057W Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mit...   1 4   0
  YCR100C     1 4   0
GGC1 YDL198C Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenanc...   1 4   0.0405
YRB1 YDR002W Ran GTpase binding protein; involved in nuclear protein import and RNA export, u...   1 16   0.002
IPT1 YDR072C Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-cer... inositolphosphotransferase 1 1 5   0.2526
  YDL186W     1 5   0
  YDL156W     1 14   0.3122
ADH7 YCR105W NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrat... medium chain alcohol dehydrogenase 1 9   0
TRM3 YDL112W 2--O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine... tRNA (Gm18) ribose methylase 1 9   0
VCX1 YDL128W Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; ... vacuolar H+/Ca2+ exchanger 1 6   0

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