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SONAR Targetspace for alpha-MANGOSTINZ-score WebGraph NB WebGraph
Targetspace hs 211 257
Targetspace hs pval0.204326923076920.29457364341085
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   15 51 -1.8093 0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 11 13   0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   11 98 -15.7141 0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   11 15   0.0524
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   11 34   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38 -13.3797 0.1393
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -28.2946 0.14
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 25 -16.6491 NAN
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 9 33   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 8 36   0.1127
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 8 45   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 8 108   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 8 24 0.9194 0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 8 143 -8.2270 0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 7 8   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   7 89   0.0002
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   7 5   0
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 7 36   0.1583
HSL1 YKL101W Nim1p-related protein kinase that regulates the morphogenesis and septin checkpo... serine-threonine kinase 7 105   0.047
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   7 49   0.0868
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   7 38   NAN
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 7 37   0
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   7 23   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 6 41   0
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 16   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 6 104 -2.0041 0.0097
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 6 38   0
  YPL077C     6 22   0.0026
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 6 29   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 6 13   0
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 5 62   0.089
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 5 27   0.079

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