Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for SELAMECTINZ-score WebGraph NB WebGraph
Targetspace hs 219 301
Targetspace hs pval0.0351239669421490.45217391304348
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 14 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 14 25   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   13 10 -15.9145 0
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   13 43   NAN
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 12 27   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 10 13   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   10 33 -1.7624 0.0321
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   9 22   0
KOG1 YHR186C Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that ...   9 35   0
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   9 14 -6.8358 0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 8 33   0
MYO3 YKL129C One of two type I myosins; localizes to actin cortical patches; deletion of MYO3... myosin I 8 54   0
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   7 12   0
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   7 45   NAN
  YKL161C     7 18   0.1504
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 7 18   0.0001
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   7 28   0.0001
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   7 26   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 7 143 -5.9486 0
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   7 11   0
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   7 17   0
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   7 8   0.0082
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 7 22   0
LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi t...   6 38   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 6 13   0
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
CDC55 YGL190C Non-essential regulatory subunit B of protein phosphatase 2A; has multiple roles... protein phosphatase 2A regulatory subunit B 6 66   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
ACO1 YLR304C Aconitase, required for the tricarboxylic acid (TCA) cycle and also independentl... aconitase 6 28   0
ZUO1 YGR285C Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the S... zuotin, Z-DNA binding protein (putative) 6 50   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   6 31   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   6 39   0
JJJ3 YJR097W Protein of unknown function, contains a J-domain, which is a region with homolog...   5 11   0
EBP2 YKL172W Essential protein required for the maturation of 25S rRNA and 60S ribosomal subu... nucleolar protein 5 73   0
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   5 42   0.0127
  YJR141W     5 12   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 5 38 -1.0771 0.0253
MRM1 YOR201C Ribose methyltransferase that modifies a functionally critical, conserved nucleo... ribose methyltransferase for mitochondrial 21S rRNA 5 11   0
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing; associates with trans-ac...   5 67   0

Service provided by the Mike Tyers Laboratory