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SONAR Targetspace for ESTRONE HEMISUCCINATEZ-score WebGraph NB WebGraph
Targetspace hs 254 172
Targetspace hs pval0.0287474332648870.048117154811715
XgmmL File for compound download download
Stats file for targetspace download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   6 10   0
RIX7 YLL034C Putative ATPase of the AAA family, required for export of pre-ribosomal large su...   3 60   0
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases with similarity to ...   3 57   0
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 2 53   0.0018
DHH1 YDL160C Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct...   2 53   0.0456
YPT6 YLR262C GTPase, Ras-like GTP binding protein involved in the secretory pathway, required... similar to the human GTPase, Rab6 2 35 -5.3064 0
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex, which is involved in regulati...   2 57   0
LSM2 YBL026W Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNA-associated protein, Sm class 2 101   0
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 2 41   0.0046
MPS1 YDL028C Dual-specificity kinase required for spindle pole body (SPB) duplication and spi...   2 70   0.2734
COF1 YLL050C Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds ... actin binding and severing protein|cofilin 2 40   0.018
MYO3 YKL129C One of two type I myosins; localizes to actin cortical patches; deletion of MYO3... myosin I 2 54   0.0421
NOT3 YIL038C Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... CCR4 transcriptional complex component 2 31   0.2012
NHP10 YDL002C Protein related to mammalian high mobility group proteins; likely component of t... HMG1-box containing protein 2 51   0.1557
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   2 39   0.069
YAK1 YJL141C Serine-threonine protein kinase that is part of a glucose-sensing system involve...   2 69   0.0034
CAF130 YGR134W Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex...   2 23   0.0145
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 2 5   0
CDC36 YDL165W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 2 34   0.0419
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and ... glyceraldehyde-3-phosphate dehydrogenase 3 2 56   0
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 2 30   0.1703
  YPR115W     2 38   0
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 2 27   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 2 13   0.0684
  YBR225W     2 13   0.0004
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 2 25   0
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 2 94   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   2 33 -5.3877 0
CDC11 YJR076C Component of the septin ring of the mother-bud neck that is required for cytokin... 10 nm filament component of mother-bud neck|septin 2 66   0.0168
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   2 43   0
MBR1 YKL093W Protein involved in mitochondrial functions and stress response; overexpression ...   1 18   0
AVT3 YKL146W Vacuolar transporter, exports large neutral amino acids from the vacuole; member... Gln (Asn), Ile (Leu), Tyr transporter 1 11   0
EDC3 YEL015W Non-essential conserved protein of unknown function, plays a role in mRNA decapp...   1 44   0
  YJR141W     1 12   0
MNR2 YKL064W Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate...   1 15   0
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlap... protein disulfide isomerase homolog 1 3   0
  YKL171W     1 64   0

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