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SONAR Targetspace for ESTRONE HEMISUCCINATEZ-score WebGraph NB WebGraph
Targetspace hs 254 172
Targetspace hs pval0.0287474332648870.048117154811715
XgmmL File for compound download download
Stats file for targetspace download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 9 80   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   8 89   0
  YIL039W     7 115   0
RAV2 YDR202C Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 dom...   6 103   0.1636
MRL1 YPR079W Membrane protein with similarity to mammalian mannose-6-phosphate receptors, pos...   6 55   0.174
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   5 96   0
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   5 42   0.0665
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline... clathrin assembly complex beta adaptin component (putative) 5 98   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   5 104   0.1694
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   5 79   0.1876
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 5 71   0
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 4 107   0
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved... ARF GTP/GDP exchange factor 4 38   0.1894
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   4 112   0.1764
  YPR148C     4 14   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   4 109   0.1995
  YPR114W     4 19   0
  YER113C     4 22   0
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 4 46   0
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence...   4 95   0
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 4 96   0.0151
  YGR266W     4 31   0.1644
PCT1 YGR202C Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidyly... cholinephosphate cytidylyltransferase|phosphorylcholine transferase 4 47   0
FMO1 YHR176W Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER mem... flavin-containing monooxygenase 4 23   0.0174
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapam... peptidyl-prolyl cis-trans isomerase (PPIase) 4 131   0.0009
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 4 147   0
OLE1 YGL055W Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for... delta-9-fatty acid desaturase 4 99   0.0002
KRE27 YIL027C Protein of unknown function; null mutant shows K1 killer toxin resistance   4 93   0.0004
SVP26 YHR181W Integral membrane protein of the early Golgi apparatus, may function to promote ... integral membrane protein 4 69   0
  YPR003C     4 23   0
GOT1 YMR292W Evolutionarily conserved non-essential protein present in early Golgi cisternae ... membrane protein 4 76   0
  YOL107W     4 19   0
PBP1 YGR178C Protein interacting with poly(A)-binding protein Pab1p; likely involved in contr...   4 123   0.0016
SHR5 YOL110W Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palm...   4 31   0.1422
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP; genetic interactions w...   4 35   0.0408
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing, interacts with Si...   4 51   0
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 4 79   0

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