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SONAR Targetspace for PARTHENOLIDEZ-score WebGraph NB WebGraph
Targetspace hs 102 346
Targetspace hs pval0.141230068337130.052521008403361
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 13 67 -1.2527 0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   11 30   0.011
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   10 41   0
MVP1 YMR004W Protein required for sorting proteins to the vacuole; overproduction of Mvp1p su...   9 16   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 8 108   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   8 32   0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   8 21   0.0076
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 8 56   0.0034
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 7 24   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 7 76   NAN
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   7 97   0.0005
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in tr... v-SNARE 7 14   0.1648
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   7 31   0.0067
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   7 100   0
TLG2 YOL018C Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fus... tSNARE that affects a late Golgi compartment 7 128   0
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   7 47   0.0809
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   7 110   0.0071
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   7 73   0.0565
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   7 41   0
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 7 65 -3.6235 0.1014
GMH1 YKR030W Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; requ...   6 5   0.1295
RPL16B YNL069C N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L16B (L21B) (rp23) (YL15) 6 14   0.1069
SEC21 YNL287W Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p... PEST sequence-containing protein|non-clathrin coat protein 6 26   0.0001
SLY1 YDR189W Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM... t-SNARE-interacting protein that functions in ER-to-Golgi traffic 6 38   0.1407
  ETG9627     6 5   0
VPS29 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex ...   6 52   0.0222
  YPR084W     6 4   0.0025
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   6 25   0.145
IMH1 YLR309C Protein involved in vesicular transport, mediates transport between an endosomal...   6 4   0.0005
DCR2 YLR361C Putative phosphoesterase that functions as a dosage-dependent positive regulator...   6 19   0
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 5 19   0
BUD6 YLR319C Actin- and formin-interacting protein, involved in actin cable nucleation and po...   5 36   0.0003
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts p... phosphatidylserine decarboxylase 5 45   0.1488
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   5 57   0
ENT4 YLL038C Protein of unknown function, contains an N-terminal epsin-like domain   5 4   0.0473
EMP70 YLR083C Protein whose 24kDa cleavage product is found in endosome-enriched membrane frac...   5 7   0.0767
  YMR010W     5 4   0

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