Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for METHIOTHEPIN MALEATEZ-score WebGraph NB WebGraph
Targetspace hs 319 286
Targetspace hs pval0.28791773778920.032989690721649
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   13 98 -17.0226 0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 13 143 -9.0322 0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   13 51   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   12 109   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 11 33   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   11 15   0.0524
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -4.1143 0.14
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   10 38   NAN
CDC73 YLR418C Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rt...   9 61 -10.6814 0.0001
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 9 25 -18.0513 NAN
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 9 24   0
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 8 36   0.1592
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   8 49   0.0464
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   7 80   0
  YFR038W     7 7   0.001
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 7 25   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 7 108   0
CLA4 YNL298W Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) fam... Ste20p homolog|protein kinase 6 68 -0.9446 0
ILV5 YLR355C Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-ch... acetohydroxyacid reductoisomerase 6 17   0
  YPL077C     6 22   0.0026
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   6 89   0.0013
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... isocitrate dehydrogenase 1 alpha-4-beta-4 subunit 6 17   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   6 34   0
GAL7 YBR018C Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UD... galactose-1-phosphate uridyl transferase 6 9   0
PMA1 YGL008C Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cyt... plasma membrane H+-ATPase 6 50   0.0157
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide ... Hsp70 family 5 16   0.1056
GCN3 YKR026C Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide... eIF2B 34 kDa alpha subunit 5 52   0
ASC1 YMR116C WD repeat protein (G-beta like protein) involved in translation regulation; requ... G-beta like protein 5 73   0.0013
SKG3 YLR187W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   5 16   0
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 5 38   0.006
QCR2 YPR191W Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component ... 40 kDa ubiquinol cytochrome-c reductase core protein 2 5 24   0

Service provided by the Mike Tyers Laboratory