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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:34
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 14 25 -19.4960 NAN
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   12 34   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 11 33   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 11 24   0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   10 51   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   10 98 -43.9498 0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -4.3657 0.14
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 9 143 -17.8817 0
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 9 104   0.059
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   9 89   0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 8 51   0
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   8 23   0
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 7 29   0
  YPL077C     7 22   0.0005
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   7 5   0
PRE3 YJL001W 20S proteasome beta-type subunit, responsible for cleavage after acidic residues... 20S proteasome subunit 6 39   0
SIR3 YLR442C Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tai... silencing regulator at HML, HMR, and telomeres 6 56   0.1442
AHA1 YDR214W Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to ... Hsp90 system cochaperone; Aha1 binds to the middle domain of Hsp90 and improves client protein activation in vivo 6 51   0
MKT1 YNL085W Protein that forms a complex with Pbp1p that may mediate posttranscriptional reg... retroviral protease signature protein 6 36   0.0313
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   6 47   0.0097
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   6 109   0
TIF2 YJL138C Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helica... translation initiation factor eIF4A subunit 6 73   0
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 6 39   0.005
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   6 33   0.0277
ASC1 YMR116C WD repeat protein (G-beta like protein) involved in translation regulation; requ... G-beta like protein 6 73   0.0002
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   6 33   0.0114
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   6 32 -27.1633 0.1762
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 6 62   0.1281

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