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SONAR Targetspace for MECLOFENOXATE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 845 0
Targetspace hs pval01
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   7 43   NAN
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   7 10 5.3458 0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 6 13   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 25   0
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network; forms heterod...   5 14 6.5411 0
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly iden... chaperonin 4 144   0.1769
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   3 45   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   3 28   0.0657
YIP4 YGL198W Protein that interacts with Rab GTPases; computational analysis of large-scale p...   3 26   0
ZUO1 YGR285C Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the S... zuotin, Z-DNA binding protein (putative) 3 50   0.0001
MSB4 YOL112W GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, l...   3 11   0
YPT6 YLR262C GTPase, Ras-like GTP binding protein involved in the secretory pathway, required... similar to the human GTPase, Rab6 3 35 4.9577 0
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 3 27   0
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5...   3 12   0.0028
YOP1 YPR028W Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpr...   3 17   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   3 31   0
MRS6 YOR370C Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is... rab geranylgeranyltransferase regulatory subunit 3 22   0.0025
SGM1 YJR134C Protein of unknown function, required for wild-type growth rate on galactose and...   3 8   0.2273
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps5... hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p 3 18   0.0632
SYG1 YIL047C Plasma membrane protein of unknown function; truncation and overexpression suppr... plasma membrane protein 2 5   0
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
UFE1 YOR075W t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane... t-SNARE (ER) 2 19   0.0575
YEF3 YLR249W Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tR... Translation elongation factor 3 (EF-3) 2 94   0
RIX7 YLL034C Putative ATPase of the AAA family, required for export of pre-ribosomal large su...   2 60   0
SEC21 YNL287W Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p... PEST sequence-containing protein|non-clathrin coat protein 2 43   0.1332
BET1 YIL004C Type II membrane protein required for vesicular transport between the endoplasmi...   2 40   0.1146
LSM2 YBL026W Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either L... snRNA-associated protein, Sm class 2 101   0
YIF1 YNL263C Integral membrane protein required for the fusion of ER-derived COPII transport ...   2 39   0
COF1 YLL050C Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds ... actin binding and severing protein|cofilin 2 40   0.018
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells... EC 1.8.4.8|thioredoxin 2 24   0
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport GTPase activating protein (GAP) for Gsp1p 2 27   0.0004
SLY1 YDR189W Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM... t-SNARE-interacting protein that functions in ER-to-Golgi traffic 2 24   0.1084
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum... v-SNARE 2 32   0.1769
SED5 YLR026C cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and t... syntaxin family 2 83   0.0224
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protei... yeast coatomer subunit 1 40   0
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicl... coatomer complex gamma-alpha-COP alpha subunit 1 57   0.117
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... similar to Gcs1p and Sps18p|zinc finger protein 1 48   0.0001
FOL3 YMR113W Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the con... dihydrofolate synthetase 1 2   0
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and ... glyceraldehyde-3-phosphate dehydrogenase 3 1 56   0

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