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SONAR Targetspace for BETAMETHASONE 17,21-DIPROPIONAZ-score WebGraph NB WebGraph
Targetspace hs 267 0
Targetspace hs pval0.0591966173361521
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... endonuclease III DNA base excision repair N-glycosylase 3 23   0
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodim... ATP dependent DNA ligase 2 15   0.0596
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
REV1 YOR346W Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase ze... deoxycytidyl transferase 2 32   0.0059
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision... DNA glycosylase 2 23   0.0755
EXO1 YOR033C 5--3- exonuclease and flap-endonuclease involved in recombination, double-strand... exonuclease 2 63   0.0354
MRP17 YKL003C Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic int... ribosomal protein MRP17 2 3   0.1532
TOP2 YNL088W Essential type II topoisomerase, relieves torsional strain in DNA by cleaving an... topoisomerase II 2 15   0.166
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active...   2 60   0.2442
SIS2 YKR072C Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion ...   2 50   0.1242
TRM2 YKR056W tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs... tRNA methyltransferase 2 6   0.1154
  YER139C     2 18   0.0131
WSS1 YHR134W Sumoylated protein of unknown function, identified based on genetic interactions...   1 28   0.1079
EST3 YIL009C-A Component of the telomerase holoenzyme, involved in telomere replication 20.5 kDa 181aa protein 1 7   0
  YJL051W     1 1   0.363
REC104 YHR157W Protein involved in early stages of meiotic recombination; required for meiotic ... meiosis-specific protein 1 8   0.3147
REC107 YJR021C Protein involved in early stages of meiotic recombination; involved in altering ... ds break formation complex subunit 1 5   0.3001
RSC30 YHR056C One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; no...   1 4   0.2701
RMD9 YGL107C Mitochondrial protein required for sporulation   1 11   0.3748
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive...   1 6   0.0713
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not func...   1 8   0.0995
PUP2 YGR253C Alpha subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; ... proteasome subunit 1 7   0
AMN1 YBR158W Protein required for daughter cell separation, multiple mitotic checkpoints, and...   1 20   0.0659
SKN1 YGR143W Protein involved in sphingolipid biosynthesis; type II membrane protein with sim... highly homologous to Kre6p|type II membrane protein (putative) 1 10   0.0675
RFA1 YAR007C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... RF-A|heterotrimeric RPA (RF-A) single-stranded DNA binding protein 69 kDa subunit 1 43   0
MEI4 YER044C-A Meiosis-specific protein involved in recombination; required for chromosome syna... 88 bp intron at 5- end spliced independently of MER1|meiosis-specific protein 1 4   0
SIZ1 YDR409W SUMO ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related... chromatin protein; SUMO1/Smt3 ligase 1 40   0.3087
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family...   1 9   0.1731
MSH5 YDL154W Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers... mutS homolog 1 8   0.0405
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation as the recruit... Telomere elongation protein 1 30   0.0594
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events, activates...   1 15   0.3452
TDP1 YBR223C Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3--phosphotyrosyl bonds to generate ...   1 29   0.0082
APN2 YBL019W Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of h... AP endonuclease 1 18   0.3333
REV3 YPL167C Subunit of DNA polymerase zeta, which is involved in DNA repair; required for mu... DNA polymerase zeta subunit 1 73   0.0014
POL4 YCR014C DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p ... DNA polymerase IV 1 5   0.3333
MSH3 YCR092C Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertio... forms a complex with Msh2p to repair insertion-deletion mispairs; redundant with Pms3/Msh6p in repair of insertion-deletion mispairs|mutS homolog 1 13   0.3147
STN1 YDR082W Telomere end-binding and capping protein, plays a key role with Pol12p in linkin...   1 19   0.3205
CDC9 YDL164C DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins... DNA ligase 1 12   0.3077
RPN5 YDL147W Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to m... proteasome regulatory particle subunit 1 1   0

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