Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for CHLORPROTHIXENE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 0 0
Targetspace hs pval11
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 33 115   0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   31 54   NAN
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 30 81 -3.4372 0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 27 41 -3.3583 NAN
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   25 46   0.0611
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   23 107 -0.0546 NAN
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   22 54   NAN
CHS7 YHR142W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   22 45 -7.7278 NAN
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 22 108 -10.0860 0
  YKL161C     20 5   0.0001
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   20 16   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 20 140 -0.4626 0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 20 93 -7.8296 NAN
PKH2 YOL100W Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   19 19   0
PKH1 YDR490C Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   19 22   0
UBP3 YER151C Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde... ubiquitin-specific protease 19 99   0.0628
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   19 48   0.019
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 18 25   0.001
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 18 26 -3.6718 0.0083
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   18 64   0.0364
  YKL037W     18 12   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 18 19   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 18 104   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   17 22   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 17 28   0.0574
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent prot... high affinity cAMP phosphodiesterase 16 62   0.023
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 16 111 -0.9132 0
SKT5 YBL061C Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via int...   15 67 -6.8021 0.0007
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in m...   15 49   0
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II tran... TFIID subunit 15 116   0
RIM21 YNL294C Protein proposed to be involved in the response to alkaline pH; has similarity t... Unknown function 15 37   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   15 71 0.6521 0.0435
HOS2 YGL194C Histone deacetylase required for gene activation via specific deacetylation of l...   15 74   0.0087
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   15 93 -2.5243 0.1187
MOB1 YIL106W Component of the mitotic exit network; associates with and is required for the a...   14 22   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   14 32   0
MTL1 YGR023W Protein with both structural and functional similarity to Mid2p, which is a plas... acts in concert with Mid2p to transduce cell wall stress signals 14 11   0
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   14 62   0
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes th... dolichol phosphate mannose synthase 14 8   0

Service provided by the Mike Tyers Laboratory