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SONAR Targetspace for AMIPRILOSEZ-score WebGraph NB WebGraph
Targetspace hs 154 0
Targetspace hs pval0.0245398773006131
XgmmL File for compound download download
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Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochon... heat shock protein 78 2 39   0
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 1 25   0.2106
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlap... protein disulfide isomerase homolog 1 3   0
IPT1 YDR072C Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-cer... inositolphosphotransferase 1 1 5   0.2526
YRB1 YDR002W Ran GTpase binding protein; involved in nuclear protein import and RNA export, u...   1 16   0.002
  YDL156W     1 14   0.3122
GGC1 YDL198C Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenanc...   1 4   0.0405
NPR2 YEL062W Regulator of nitrogen permeases; transcription is induced in response to proline...   1 18   0.083
PMD1 YER132C Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 16   0.0205
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosi... plasma membrane pyridoxine transport protein 1 1   0
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation; forms complex... protein with COPI and COPII bindng motifs 1 20   0
ROG3 YFR022W Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY...   1 10   0
  YER138C     1 11   0
  YER160C     1 8   0
VCX1 YDL128W Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; ... vacuolar H+/Ca2+ exchanger 1 6   0
TRM3 YDL112W 2--O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine... tRNA (Gm18) ribose methylase 1 9   0
FUN19 YAL034C Non-essential protein of unknown function   1 13   0
MTW1 YAL034W-A Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p...   1 50   0
SRP68 YPL243W Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) ... signal recognition particle component 1 17   0
FOL3 YMR113W Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the con... dihydrofolate synthetase 1 2   0
ATE1 YGL017W Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of ar... arginyl-tRNA-protein transferase 1 8   0
  YGR043C     1 8   0
  YBL100W-A     1 1   0
CHS2 YBR038W Chitin synthase II, requires activation from zymogenic form in order to catalyze... chitin synthase 2 1 5   0.3203
ADH7 YCR105W NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrat... medium chain alcohol dehydrogenase 1 9   0
NHP10 YDL002C Protein related to mammalian high mobility group proteins; likely component of t... HMG1-box containing protein 1 51   0.0758
  YCR100C     1 4   0
PRD1 YCL057W Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mit...   1 4   0
QDR3 YBR043C Multidrug transporter required for resistance to quinidine, barban, cisplatin, a...   1 3   0
IST2 YBR086C Plasma membrane protein that may be involved in osmotolerance, localizes to the ...   1 22   0.1309
MDS3 YGL197W Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 21   0.0484
  YGR001C     1 8   0
  YOL125W     1 10   0
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body, involved in modi...   1 31   0
  YOL083W     1 18   0
  YNL217W     1 11   0
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synt... aminodeoxychorismate synthase 1 12   0
  YOL138C     1 14   0.006
CIN5 YOR028C Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pl... bZIP (basic-leucine zipper) protein|can activate transcription from a promoter containing a Yap recognition site 1 15   0.0516

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