Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for AMIPRILOSEZ-score WebGraph NB WebGraph
Targetspace hs 154 0
Targetspace hs pval0.0245398773006131
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
ATG8 YBL078C Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, a... similar to LC3, a microtubule-associated protein from rat 2 20   0
ZAP1 YJL056C Zinc-regulated transcription factor, binds to zinc-responsive promoter elements ...   2 30   0
TIR3 YIL011W Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins... cell wall mannoprotein 2 3   0
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 2 20   0.0031
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
HXT8 YJL214W Protein of unknown function with similarity to hexose transporter family members... hexose permease 2 13   0
UBX4 YMR067C UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48...   2 37   0.004
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   1 13   0.0232
CET1 YPL228W Beta (RNA 5--triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (... RNA 5--triphosphatase|mRNA capping enzyme beta subunit (80 kDa) 1 8   0.0002
UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, ... ubiquitin-specific protease 1 7   0
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   1 26   0
MDM38 YOL027C Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal...   1 8   0.0001
  YLR168C     1 10   0.0001
MRPS8 YMR158W Mitochondrial ribosomal protein of the small subunit   1 1   0.0002
VID30 YGL227W Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-...   1 5 -0.6367 0
SPT2 YER161C Protein involved in negative regulation of transcription, exhibits regulated int... non-specific DNA binding protein 1 51   0
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family, involved in activatin... putative mitochondrial carrier protein 1 2   0.0003
HIR3 YJR140C Transcriptional corepressor involved in the cell cycle-regulated transcription o...   1 17   0
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   1 19 -1.0452 0
MDM35 YKL053C-A Protein of unknown function; mutation affects mitochondrial distribution and mor...   1 6   0
PGM1 YKL127W Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosp... phosphoglucomutase minor isoform 1 11   0.073
PMD1 YER132C Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 3   0.0205
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts i... CCR4 transcriptional complex component 1 3   0
MDV1 YJL112W Peripheral protein of the cytosolic face of the mitochondrial outer membrane, re...   1 4   0
AVL9 YLR114C Mutation is syntheticly lethal with apl2 vps1 double mutant   1 3   0.0494
MGM1 YOR211C Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p a... GTP-binding domain protein related to dynamin 1 8   0.0659
ERV41 YML067C Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involve...   1 13   0
STE2 YFL026W Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that intera... G protein coupled receptor (GPCR)|alpha-factor pheromone receptor|seven-transmembrane domain protein 1 18   0.3312
RPN11 YFR004W Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid...   1 9   0.083
SNQ2 YDR011W ABC transporter protein involved in multidrug resistance and resistance to singl... ABC transporter 1 7   0
  YER139C     1 18   0.0033
ROG1 YGL144C Protein with putative serine active lipase domain   1 6   0.0205
NAT5 YOR253W Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-termin... N-acetyltransferase 1 4   0
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cer... MDS1 related protein kinase 1 6   0.0294
YGK3 YOL128C Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 famil... protein kinase 1 5   0.0002
BUL2 YML111W Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular am...   1 6   0.037
PIH1 YHR034C Protein of unresolved function; may function in protein folding and/or rRNA proc...   1 14   0.3152

Service provided by the Mike Tyers Laboratory