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SONAR Targetspace for HEMATEINZ-score WebGraph NB WebGraph
Targetspace hs 359 102
Targetspace hs pval0.27806122448980.54153846153846
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 3 62   0.0224
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 2 10   0.0043
  YPL009C     2 12   0
ULP1 YPL020C Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjug... Smt3-specific protease 2 27   0.1789
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that amin... tyrosine-tRNA ligase 2 21   0
PUS1 YPL212C tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36... tRNA pseudouridine synthase 2 10   0
MPS1 YDL028C Dual-specificity kinase required for spindle pole body (SPB) duplication and spi...   2 70   0.2734
SFL1 YOR140W Transcription repressor involved in regulation of flocculation-related genes, in... transcription factor 2 16   0
  YAR009C     2 9   0
  YKL047W     2 5   0
DOP1 YDR141C Protein of unknown function, essential for viability, involved in establishing c...   2 16   0.1881
TOP1 YOL006C Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleavin... topoisomerase I 2 47 -5.1889 0.0252
VPS5 YOR069W Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/lat... simialr to sorting nexin I 2 18 -0.4477 0.1823
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 2 38   0
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA duri... UV endonuclease 2 44   0.0007
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   2 33   0.2666
UME6 YDR207C Key transcriptional regulator of early meiotic genes, binds URS1 upstream regula... C6 zinc finger URS1-binding protein 2 40   0.1365
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   2 36   0.1762
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   2 35   0.0014
TIF3 YPR163C Translation initiation factor eIF-4B, has RNA annealing activity; contains an RN... translation initiation factor eIF-4B 2 17 1.1177 0
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   2 33   0.2866
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); fu... clathrin assembly complex AP-3 adaptin component delta-like subunit 2 24   0
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 2 39   0.2803
VAM7 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-... heptad repeat motif|hydrophilic protein 2 44   0.0376
ASH1 YKL185W Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in t...   2 42   0
TKL1 YPR074C Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate an... transketolase 1 2 18   0.1692
PEP3 YLR148W Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reac... vacuolar membrane protein 2 33   0.0237
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two ... interacts with two t-SNARES, Sed5p and Pep12p|v-SNARE 2 39   0.0138
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   2 32 -1.1969 0.0537
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 1 27   0.1895
BAS1 YKR099W Myb-related transcription factor involved in regulating basal and induced expres... transcription factor 1 11   0.3795
JNM1 YMR294W Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p...   1 19   0.0002
CIN5 YOR028C Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pl... bZIP (basic-leucine zipper) protein|can activate transcription from a promoter containing a Yap recognition site 1 15   0.0516
SPC72 YAL047C Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole b...   1 31   0.0119
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases with similarity to ...   1 57   0
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the dire... pyruvate dehydrogenase alpha subunit (E1 alpha) 1 23   0.0687
HYM1 YKL189W Component of the RAM signaling network that is involved in regulation of Ace2p a...   1 11   0.3281
ATG5 YPL149W Conserved autophagy-related protein that undergoes conjugation with Atg12p and t...   1 12   0
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis   1 26   0
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   1 7   0.0001

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