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SONAR Targetspace for FISETINZ-score WebGraph NB WebGraph
Targetspace hs 87 421
Targetspace hs pval0.318421052631580.67
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   38 98 -11.8062 0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 33 143 -8.5318 NAN
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 29 33   0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   25 51 -1.0004 0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 25 38 -13.1730 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   23 34   NAN
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   21 15   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 20 39   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 20 16   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   20 26 -5.1865 0.0017
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 19 21   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 17 25 -13.1428 NAN
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 17 36   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 17 24 -1.3351 0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 16 13   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 16 108   0
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 14 25   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   14 89   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   13 31   0.1284
RTF1 YGL244W Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly... nuclear protein 12 36   0.043
  YPL077C     12 22   0
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spin... ubiquitin-like protein 12 37   0
CTR9 YOL145C Component of the Paf1p complex, which is a large complex that binds to and modul...   12 49   0.001
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 12 8   0
KOG1 YHR186C Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that ...   11 35   0
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 11 15   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 11 41   0
USE1 YGL098W Essential SNARE protein localized to the ER, involved in retrograde traffic from...   11 19   0
LEO1 YOR123C Component of the Paf1 complex, which associates with RNA polymerase II and is in...   11 38   NAN
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 11 45   0
PMA1 YGL008C Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cyt... plasma membrane H+-ATPase 11 50   0.1212
SOG2 YOR353C Protein required for cell morphogenesis and cell separation after mitosis   10 10   0
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... isocitrate dehydrogenase 1 alpha-4-beta-4 subunit 10 17   0
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p; required for recycling Golgi ... cysteine rich putative zinc finger essential for function|hydrophilic protein 10 25   0
QCR2 YPR191W Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component ... 40 kDa ubiquinol cytochrome-c reductase core protein 2 10 24   0
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, u... phenylalanyl-tRNA synthetase alpha subunit 10 6   0
WSP1 YOR220W protein that interacts genetically with the Pat1 mRNA-decapping factor   10 8   0
MPM1 YJL066C Mitochondrial membrane protein of unknown function, contains no hydrophobic stre...   10 11   0
SKG3 YLR187W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   10 16   0

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