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SONAR Targetspace for FISETINZ-score WebGraph NB WebGraph
Targetspace hs 87 421
Targetspace hs pval0.318421052631580.67
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 17 51   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 13 66   0
PIR1 YKL164C O-glycosylated protein required for cell wall stability; attached to the cell wa...   12 36   0
  YKL161C     12 35   0.0526
SDP1 YIL113W Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates S...   11 13   0
LST4 YKL176C Protein possibly involved in a post-Golgi secretory pathway; required for the tr...   11 128   0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 95   0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   10 44   0
  YKL037W     9 16   0.0048
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   9 38   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   9 23   0.0083
  YOL019W     8 18   0
SLN1 YIL147C Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane p... histidine kinase osmosensor that regulates an osmosensing MAP kinase cascade|similar to bacterial two-component regulators 8 34   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 8 36   0
ROM1 YGR070W GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal wit...   8 31   0
ACK1 YDL203C Hypothetical protein a TRP/SEL-1 domain containing protein 7 53   0
YPD1 YDL235C Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor ... two-component phosphorelay intermediate 7 91   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   7 47   0.1639
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   7 147   0.0001
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 7 14   0.0465
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 7 33   0
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 6 49   0.0003
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 46   0
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 25   0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 6 46   0.0643
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 28   0
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 6 39   0
  YPL077C     6 26   0.0026
MEH1 YKR007W Component of the EGO complex, which is involved in the regulation of microautoph...   6 131   0.0001
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   6 31   0.091
MKS1 YNL076W Pleiotropic regulatory factor involved in Ras-CAMP and lysine biosynthetic pathw... negative transcriptional regulator 6 142   0
  YDR348C     6 31   0
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   6 77   0.0879
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 6 113   0
GPI11 YDR302W ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI...   5 2   0
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to... UDP-N-acetyl-glucosamine-1-P transferase (GPT) 5 22   0
EBS1 YDR206W Protein of unknown function, contains a putative RNA recognition motif, deletion...   5 24   0
MSC2 YDR205W Member of the cation diffusion facilitator family, localizes to the endoplasmic ...   5 24   0

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