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SONAR Targetspace for FISETINZ-score WebGraph NB WebGraph
Targetspace hs 87 421
Targetspace hs pval0.318421052631580.67
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 31 108 -1.4694 NAN
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   31 140   0
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   28 46   0.0223
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   28 54   NAN
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   27 102   0
  YKL037W     26 12   0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 26 115   0
  YKL161C     25 5   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   25 16   0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 24 126 -2.8749 0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 23 41 -6.3404 NAN
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   23 62   NAN
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 22 16   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 22 28   0.1032
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   21 65   0.0025
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 21 104   0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 21 93 -1.8058 NAN
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   20 93 -4.0864 0.056
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   20 10   0.0003
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   20 32   0
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   20 107 -4.4718 NAN
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 20 9   0
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 20 92 -0.3351 0.0283
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 19 62   0.017
URM1 YIL008W Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends ... ubiquitin-like protein 19 56   0
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 19 64 -5.4459 0.1014
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 18 19   0
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   18 31 -1.3176 0.0006
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 18 29   0
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 18 109 -0.8769 NAN
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   18 80 -0.9729 NAN
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 18 27   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 17 89 -8.5318 NAN
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   17 24   0
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   17 72   0.0001
CDC34 YDR054C Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F... ubiquitin-conjugating enzyme 16 58   0
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activi...   16 26   0.044

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