Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for CAMPTOTHECINZ-score WebGraph NB WebGraph
Targetspace hs 581 505
Targetspace hs pval00.030612244897959
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:27
Sym Orf Description Function No All Z_score hyperg
YAK1 YJL141C Serine-threonine protein kinase that is part of a glucose-sensing system involve...   8 69   0
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 4|similar to human RFC 40 kDa subunit 6 34   0.0001
POL30 YBR088C Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DN... Proliferating Cell Nuclear Antigen (PCNA) 6 61   0.0015
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 5|similar to human RFC 38 kDa subunit 6 37   0.0707
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   5 109   0
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 3|similar to human RFC 36 kDa subunit 5 33   0
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding ... replication factor C subunit 2|similar to human RFC 37 kDa subunit 5 39   0
VAM3 YOR106W Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in... syntaxin family 4 40 -19.2269 0
CAF130 YGR134W Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex...   4 23   0
NOT3 YIL038C Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... CCR4 transcriptional complex component 4 31   0.1981
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   4 39   0.1772
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   4 36   0.2065
VPS33 YLR396C ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuol...   4 35   0
CTF4 YPR135W Chromatin-associated protein, required for sister chromatid cohesion; interacts ... DNA polymerase alpha binding protein 4 38   0
PEP3 YLR148W Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reac... vacuolar membrane protein 4 33   0.0001
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 4 30   0.2086
VAM6 YDL077C Vacuolar protein that plays a critical role in the tethering steps of vacuolar m...   4 39   0.2049
CTF8 YHR191C Subunit of a complex with Ctf18p that shares some subunits with Replication Fact...   4 11   0
CDC39 YCR093W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 4 53   0.0169
RAD51 YER095W Strand exchange protein, forms a helical filament with DNA that searches for hom... Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer|RecA homolog 4 56   0
RFA1 YAR007C Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserv... RF-A|heterotrimeric RPA (RF-A) single-stranded DNA binding protein 69 kDa subunit 4 108   0
CDC36 YDL165W Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA l... transcriptional regulator 4 34   0.1393
CLA4 YNL298W Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) fam... Ste20p homolog|protein kinase 3 68 -11.3897 0
MMS1 YPR164W Protein likely involved in protection against replication-dependent DNA damage; ...   3 19   0.0313
BTT1 YDR252W Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex (alph...   3 11   0
NAP1 YKR048C Protein that interacts with mitotic cyclin Clb2p; required for the regulation of... nucleosome assembly protein I 3 120   0.0038
SSN8 YNL025C Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphory... C-type cyclin|associates with the Ssn3p cyclin-dependent kinase 3 50   0.0025

Service provided by the Mike Tyers Laboratory