Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for ANTIMYCIN A (A1 shown)Z-score WebGraph NB WebGraph
Targetspace hs 364 170
Targetspace hs pval00.048117154811715
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 6 13   0
PBS2 YJL128C MAP kinase kinase that plays a pivotal role in the osmosensing signal-transducti... MAP kinase kinase (MEK)|may act as a scaffolding protein for Sho1p, Ste11p, and Hog1p 6 38   0
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
SIC1 YLR079W Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, pre...   6 45   0
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 6 13   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
RCK2 YLR248W Protein kinase involved in the response to oxidative and osmotic stress; identif...   6 48   0
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 16   0
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex, a histone... Ada/Gcn5 protein complex member|transcription factor 5 49   0.003
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 5 108   0.0019
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-l... probable member of histone acetyltransferase SAGA complex|transcription factor 5 57   0.0002
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interact... histone acetyltransferase SAGA complex member|transcription factor 5 46   0
NSR1 YGR159C Nucleolar protein that binds nuclear localization sequences, required for pre-rR... nuclear localization sequence binding protein 5 44   0
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex, involved in maintaining ... histone acetyltransferase SAGA complex member|transcription factor 5 52   0
SIN4 YNL236W Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme... RNA polymerase II holoenzyme/mediator subunit 4 64   0.061
DST1 YGL043W General transcription elongation factor TFIIS, enables RNA polymerase II to read... RNA polymerase II elongation factor|Transcription elongation factor S-II (TFIIS)|transcription elongation factor 4 38   0.1279
  YGR058W     3 12   0.0001
PTC2 YER089C Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress ... protein phosphatase type 2C 3 15   0.0005
CDC7 YDL017W DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and re... Cdc7p-Dbf4p kinase complex catalytic subunit 3 53   0.0853
KIN28 YDL108W Serine/threonine protein kinase, subunit of the transcription factor TFIIH; invo...   3 56   0
CDC37 YDR168W Essential Hsp90p co-chaperone; necessary for passage through the START phase of ...   3 40   0
RSC3 YDR303C One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; es...   3 65   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 3 8   0
SPT4 YGR063C Protein that forms a complex with Spt5p and mediates both activation and inhibit... transcriptional regulator|zinc finger protein 3 37   0.0103
RPL42A YNL162W Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and... ribosomal protein L42A (YL27) (L41A) 3 12   0
RPD3 YNL330C Histone deacetylase; regulates transcription and silencing histone deacetylase 3 62   0.0224
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   3 17   0
CDC54 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-...   3 57   0
RSC9 YML127W One of 15 subunits of the -Remodel the Structure of Chromatin- (RSC) complex; DN...   3 34   0.0021
CDC45 YLR103C DNA replication initiation factor; recruited to MCM pre-RC complexes at replicat... chromosomal DNA replication initiation protein 3 35   0.1509
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   3 31   0.0005
SCH9 YHR205W Protein kinase that regulates signal transduction activity and G1 progression, c... cAMP-dependent protein kinase homolog|suppressor of cdc25ts 3 25   0
STH1 YIL126W ATPase component of the ATP-dependent RSC chromatin remodeling complex required ... helicase related protein|snf2 homolog 3 82   0.0864
TPK3 YKL166C Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant c... cAMP-dependent protein kinase catalytic subunit 3 105   0.0018
CKA2 YOR061W Alpha- catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles... protein kinase CK2 alpha- subunit 3 128 -3.7854 0

Service provided by the Mike Tyers Laboratory