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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:33
Sym Orf Description Function No All Z_score hyperg
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   12 98 -42.3354 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   12 34   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 11 33   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 11 25 -17.9402 NAN
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 -37.6116 0.14
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 10 21   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 10 143 -14.9995 0
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 10 39   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 10 24   0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 10 36   0.0391
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   10 15   0.0832
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38   0.1393
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   10 51   0
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which cataly... isocitrate dehydrogenase 1 alpha-4-beta-4 subunit 8 17   0
RPT3 YDR394W One of six ATPases of the 19S regulatory particle of the 26S proteasome involved...   7 99   0
LYS12 YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for t... homo-isocitrate dehydrogenase 7 51   0
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of o... inorganic pyrophosphatase 7 41   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   7 109   0
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerat... 6-phosphogluconate dehydrogenase 7 29   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   6 89   0.0013
ASC1 YMR116C WD repeat protein (G-beta like protein) involved in translation regulation; requ... G-beta like protein 6 73   0.0002
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 6 104   0.0097
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 6 74   NAN
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 6 45   0.0003
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains...   6 23   0
PIL1 YGR086C Integral membrane protein that along with Lsp1p is a primary component of eisoso...   6 80   0
EGD2 YHR193C Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) in... GAL4 enhancer protein|nascent-polypeptide-associated complex human alpha NAC subunit homolog 6 33   0
ILV5 YLR355C Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-ch... acetohydroxyacid reductoisomerase 6 17   0
CBF5 YLR175W Component of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), pr... major low affinity 55 kDa centromere/microtubule binding protein 6 117   0.0001
  YPL077C     6 22   0.0026
AHA1 YDR214W Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to ... Hsp90 system cochaperone; Aha1 binds to the middle domain of Hsp90 and improves client protein activation in vivo 5 51   0
DIG1 YPL049C Regulatory protein of unknown function, constitutively-expressed, involved in th... MAP kinase-associated protein 5 54   0

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