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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 19 145 -17.9402 NAN
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 17 93   NAN
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   17 62   0
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 17 92 -28.1228 0.0839
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   16 107 -37.0272 0
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 16 62   0.0659
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 16 81 -31.1020 0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 15 140   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 14 41 -24.8082 NAN
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   14 140   0
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 13 29   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   13 64   0.1284
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 13 108 -49.1510 0
HOC1 YJR075W Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit... mannosyltransferase (putative) 13 64 -13.2388 0.0604
SKT5 YBL061C Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via int...   12 67   0
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   12 54   NAN
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 12 126 -15.3418 0
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 11 115   0.0004
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 11 111 -8.7073 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   11 54   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 11 104   0
ALG8 YOR067C Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the do... glycosyl transferase 11 89   0.0002
ALG6 YOR002W Glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyro... glucosyltransferase 11 78   0.1365
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 11 110   0.0383
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 11 46   0
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   11 102   0.1354
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 10 99   NAN
  YKL161C     10 5   0.1116
  YKL037W     10 12   0.0015
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   10 65   0.1272
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   10 93 -23.2597 0.0321
MNN2 YBR015C Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-l... golgi alpha-1,2-mannosyltransferase (putative) 10 41   0.0019
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 10 27   0
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 10 16   0

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