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SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:37
Sym Orf Description Function No All Z_score hyperg
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 17 145 -12.4945 NAN
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 16 104   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 15 46   0
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   14 107 -12.2493 0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 12 126 -10.5607 0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 12 93 -6.8416 0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 11 81 -6.5738 0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 11 140 -2.7432 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   11 54   0
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 10 41 -12.9096 NAN
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   10 16   0.0029
  YKL037W     10 12   0.0015
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31 -1.1714 0.1159
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   10 64   0.0942
  YKL161C     10 5   0.1116
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 10 28   0.0012
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   9 102   0.1041
PCL1 YNL289W Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic ce... G1 cyclin|associates with PHO85 9 25   0.1444
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 9 108 -3.5738 0
ARP2 YDL029W Essential component of the Arp2/3 complex, which is a highly conserved actin nuc... actin related protein 9 99   NAN
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 9 110   0.1028
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   9 62   0
PCL2 YDL127W G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to... G1 cyclin 9 19   0.0012
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 9 16   0
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 8 27   0
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 8 110 -2.9508 0
CHS6 YJL099W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   8 54   NAN
ARC40 YBR234C Essential subunit of the ARP2/3 complex, which is required for the motility and ...   8 44   NAN
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   8 10   0.1437
ERG11 YHR007C Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol ... cytochrome P450 lanosterol 14a-demethylase 8 79   0.1044
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   8 71 -3.2959 0.1083
OPI3 YJR073C Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), cat... unsaturated phospholipid N-methyltransferase 8 126   NAN
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   8 46   0.0003
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 8 84   0
SMY1 YKL079W Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-term... kinesin heavy chain homolog 8 29   0
SEC66 YBR171W Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with... glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins 7 109 -2.2417 NAN

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