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SONAR Targetspace for ESTRADIOL PROPIONATEZ-score WebGraph NB WebGraph
Targetspace hs 257 227
Targetspace hs pval0.0203665987780040.10352422907489
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
PAF1 YBR279W RNA polymerase II-associated protein, defines a large complex that is biochemica...   13 51 0.2274 0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   13 98 -10.4568 0
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   13 34   0
RLM1 YPL089C MADS-box transcription factor, component of the protein kinase C-mediated MAP ki...   11 15   0.0524
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 11 13   0
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 10 16   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   10 26 0.0676 0.14
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 10 38 -14.8454 0.1393
STE12 YHR084W Transcription factor that is activated by a MAP kinase signaling cascade, activa... transcription factor 9 39   0
ADA2 YDR448W Transcription coactivator, component of the ADA and SAGA transcriptional adaptor... transcription factor 9 108   0
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for... MAP kinase 9 21   0
LGE1 YPL055C Protein of unknown function; null mutant forms abnormally large cells   8 57 -7.6339 0
KOG1 YHR186C Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that ...   8 35   0
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   8 31   0.0001
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 8 33   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   8 89   0
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 8 143 -10.4540 0
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, his... ribose-phosphate pyrophosphokinase 8 25   0
PTP3 YER075C Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 8   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 7 24 -1.1483 0
SWI6 YLR182W Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1... transcription factor 7 36   0.1542
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   7 27 -11.0927 0
HRP1 YOL123W Subunit of cleavage factor I, a five-subunit complex required for the cleavage a... cleavage and polyadenylation factor CF I component involved in pre-mRNA 3--end processing 7 45   0
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 6 25 -8.7543 NAN
RXT2 YBR095C Protein possibly involved in cell fusion and invasive growth   6 33   0.0114
HOT1 YMR172W Transcription factor required for the transient induction of glycerol biosynthet... nuclear protein 6 16   0
SKO1 YNL167C Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that for...   6 16   0
SDS3 YIL084C Component of the Rpd3p/Sin3p deacetylase complex required for its structural int...   6 33   0.0277
TOR1 YJR066W PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha... phosphatidylinositol kinase homolog 6 104 -6.9525 0.0097
NHA1 YLR138W Na+/H+ antiporter involved in sodium and potassium efflux through the plasma mem...   6 8   0
  YPL077C     6 22   0.0026
SMP1 YBR182C Putative transcription factor involved in regulating the response to osmotic str...   6 11   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 6 13   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 6 25   0
SIN3 YOL004W DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in tran... DNA binding protein|involved in transcriptional regulation 6 75   0
UME1 YPL139C Negative regulator of meiosis, required for repression of a subset of meiotic ge... transcriptional modulator 6 39   0.005
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane with two pore domains... outward-rectifier potassium channel 6 3   0.0006
LST8 YNL006W Protein required for the transport of amino acid permease Gap1p from the Golgi t...   6 38   0
GCN3 YKR026C Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide... eIF2B 34 kDa alpha subunit 5 52 -1.4043 0

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