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SONAR Targetspace for ESTRADIOL PROPIONATEZ-score WebGraph NB WebGraph
Targetspace hs 257 227
Targetspace hs pval0.0203665987780040.10352422907489
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 16 81 -0.2851 0
ELP3 YPL086C Histone acetyltransferase subunit of the Elongator complex, which is a component... RNA polymerase II Elongator subunit|histone acetyltransferase 12 137   0.0912
IKI3 YLR384C Subunit of RNA polymerase II elongator histone acetyltransferase complex, involv...   12 80 -0.3028 NAN
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   11 46   0.004
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   11 65   0.1333
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 10 16   0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   10 32   0
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   10 102   0.1255
  YKL161C     10 5   0.1116
ELP4 YPL101W Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subun... RNA polymerase II Elongator protein subunit 10 80   0.0006
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates g...   9 16   0
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   9 16   0.0083
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex under low-sa...   9 29   0
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 9 28   0.0005
PTP2 YOR208W Phosphotyrosine-specific protein phosphatase involved in the inactivation of mit... tyrosine phosphatase 8 28   0
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in con... GTPase activating protein (GAP) (putative) 8 22   0
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins, involved in estab... GTP-binding protein|rho subfamily 8 50   0.1504
MSG5 YNL053W Dual-specificity protein phosphatase required for maintenance of a low level of ... protein tyrosine phosphatase 8 14   0
OPI1 YHL020C Transcriptional regulator of a variety of genes; phosphorylation by protein kina...   8 22   0
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely... rho GTPase 7 8   0.0465
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   7 72   0.1668
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   7 31 -0.1305 0.1484
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 7 14   0
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 7 7   0
ROM2 YLR371W GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically ...   7 71 0.0676 0.0787
  YKL037W     7 12   0.0347
HOS2 YGL194C Histone deacetylase required for gene activation via specific deacetylation of l...   6 74   0
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 6 27   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   6 12   0.0049
MOT1 YPL082C Essential abundant protein involved in regulation of transcription, removes Spt1... helicase (putative) 6 28   0.0748
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated co...   6 24   0.0012
ITR1 YDR497C Myo-inositol transporter with strong similarity to the minor myo-inositol transp... myo-inositol transporter 6 24   0
SAC1 YKL212W Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein traf... phosphoinositide phosphatase 6 64   NAN
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 6 41 -6.6802 0
SGD1 YLR336C Essential nuclear protein with a possible role in the osmoregulatory glycerol re...   6 4   0
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways... MAP kinase 6 26   0
MSB2 YGR014W Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filament... integral membrane protein (putative) 6 20   0
ELP6 YMR312W Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subun... RNA polymerase II Elongator protein subunit 6 73   0

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