Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for PRAMOXINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 96 352
Targetspace hs pval0.198564593301440.061440677966102
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:30
Sym Orf Description Function No All Z_score hyperg⇓
SAP30 YMR263W Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is in...   5 136 -1.8977 0.1879
VAN1 YML115C Component of the mannan polymerase I; forms a complex with Mnn9p, which is invol... mannosyltransferase 6 23   0.1768
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   6 30   0.1691
STP22 YCL008C Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorti... putative ubiquitin receptor 7 91   0.161
VPS21 YOR089C GTPase required for transport during endocytosis and for correct sorting of vacu... small GTP-binding protein 7 42   NAN
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 5 72   0.1552
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 6 27   0.1014
SUR1 YPL057C Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synth... integral membrane protein 8 40   0.0452
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 5 65 -0.8754 0.0393
SRO9 YCL037C Cytoplasmic RNA-binding protein that associates with translating ribosomes; invo...   5 30   0.0388
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   7 21   0.0218
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxy...   6 31   0.0217
SLA1 YBL007C Cytoskeletal protein binding protein required for assembly of the cortical actin... cytoskeletal protein binding protein 6 52   0.0153
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   8 59   0.008
ERG2 YMR202W C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to ... C-8 sterol isomerase 6 109   0.0078
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 56   0.0014
PAB1 YER165W Poly(A) binding protein, part of the 3--end RNA-processing complex, mediates int... poly(A) binding protein 6 25   0.0011
SKY1 YMR216C SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabo...   7 97   0.0005
RPA34 YJL148W RNA polymerase I subunit A34.5   8 41   0.0004
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   5 41   0
COG6 YNL041C Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cyt...   6 57   0
ERV14 YGL054C Protein localized to COPII-coated vesicles, involved in vesicle formation and in... 14 kDa protein found on ER-derived vesicles 6 76   0
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   5 56   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 5 67 -20.3104 0
Mon2 YNL297C Peripheral membrane protein with a role in endocytosis and vacuole integrity, in...   5 54   0
NHX1 YDR456W Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; req... Na+/H+ exchanger 6 61   0
PIK1 YNL267W Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosp... phosphatidylinositol 4-kinase 6 108   0
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   7 32   0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   10 48   0
SYS1 YJL004C Integral membrane protein of the Golgi required for targeting of the Arf-like GT...   5 41   0

Service provided by the Mike Tyers Laboratory