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SONAR Targetspace for MEBENDAZOLEZ-score WebGraph NB WebGraph
Targetspace hs 321 314
Targetspace hs pval00
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 5 homolog (putative) 10 14   0
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex involved in the fol... bovine NABC complex component homolog|non-native actin binding complex polypeptide 6|prefoldin complex subunit 10 20   0
PFD1 YJL179W Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and trans... bovine prefoldin subunit 1 homolog (putative) 9 19   0
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 2 homolog (putative) 8 11 -38.4164 0
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling, component of chr... actin related protein 6 79   0.0015
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes effi... bovine NABC complex component homolog|non-native actin binding complex polypeptide 3|prefoldin complex subunit 6 20 -24.5761 0
VPS71 YML041C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   6 28   0
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex which binds specifi... bovine prefoldin subunit 4 homolog (putative) 6 18 -28.9662 0
SWC4 YGR002C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   5 49   0
VPS72 YDR485C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   5 26   0
SWC3 YAL011W Protein of unknown function, component of the Swr1p complex that incorporates Ht...   5 30   0
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 4 20   0
YAF9 YNL107W Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 compl...   4 54   0
STU2 YLR045C Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates micro...   4 31   0
HTZ1 YOL012C Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 compl... evolutionarily conserved member of the histone H2A F/Z family of histone variants 3 87 -3.4141 0
SWC7 YLR385C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   3 23   0.0029
ARP6 YLR085C Nuclear actin-related protein involved in chromatin remodeling, component of chr...   3 24   0
BIM1 YER016W Microtubule-binding protein that together with Kar9p makes up the cortical micro...   3 39 -3.3837 0
ERV25 YML012W Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member ... vesicle coat component 3 37   0
BDF1 YLR399C Protein involved in transcription initiation at TATA-containing promoters; assoc...   3 47   0.1762
BRE1 YDL074C E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, r...   2 27 -1.8104 0
SNF4 YGL115W Protein kinase activator found in a complex containing Snf1p and members of the ... associates with Snf1p 2 51   0
PKH2 YOL100W Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   2 51   0
SAM1 YLR180W S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP...   2 90   0.2114
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoin... meiosis-specific serine/threonine protein kinase 2 65   0.0001
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ... ubiquitin ligase subunit 2 43   0
PSK2 YOL045W One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates ... PAS kinase 2 31   0.0959
TFP1 YDL185W Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding ... protein with three regions (ABC) that are spliced to yield the extein AC and the intein B; AC is a 69K vacuolar (H+)-ATPase, and B is a 50K site-specfic endonuclease named VDE (PI-SceI) that is homologous to HO. Cleavage is meiosis-specific and induces ge|site-specific endonuclease VDE (PI-SceI)|vacuolar ATPase V1 domain subunit A (69 kDa) 2 74 1.8132 0.0019
BST1 YFL025C GPI inositol deacylase of the ER that negatively regulates COPII vesicle formati...   2 3   0
  YHR113W     2 21   0
RGA2 YDR379W GTPase-activating protein for the polarity-establishment protein Cdc42p; implica... Rho-GTPase Activating Protein 2 25   0.0285
CBF2 YGR140W Essential kinetochore protein, component of the CBF3 multisubunit complex that b... centromere binding factor CBF3 110 kDa subunit 2 39   0.2006
SWC5 YBR231C Protein of unknown function, component of the Swr1p complex that incorporates Ht...   2 24 -33.4682 0
SWR1 YDR334W Swi2/Snf2-related ATPase, component of the SWR1 complex; required for the incorp...   2 37 -15.2801 0
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex under low-sa...   2 21   0
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   2 101   0.0662
ARP1 YHR129C Actin-related protein of the dynactin complex; required for spindle orientation ...   2 15 -1.4499 0.0094
ALF1 YNL148C Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP locali... tubulin folding cofactor B 2 7   0.1686

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