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SONAR Targetspace for MEBENDAZOLEZ-score WebGraph NB WebGraph
Targetspace hs 321 314
Targetspace hs pval00
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
CIN2 YPL241C Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; is... tubulin folding cofactor C 14 64 -52.2206 NAN
RBL2 YOR265W Protein involved in microtubule morphogenesis, required for protection from exce... tubulin folding cofactor A 13 30 -1.1149 NAN
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as m... tubulin folding cofactor D 11 94   0
TUB3 YML124C Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which... alpha-tubulin 10 56 -47.2019 0
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant... GTP-binding protein 10 26   0
MAD1 YGL086W Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated ...   10 134 0.0730 0.0047
EAF3 YPR023C Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase co...   9 106   0.0009
MED1 YPR070W Subunit of the RNA polymerase II mediator complex; associates with core polymera... essential for transcriptional regulation|mediator complex subunit 1 8 39   0
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation, binds alpha-tub... tubulin folding cofactor E 7 42   NAN
PNT1 YOR266W Mitochondrial inner membrane protein involved in export of proteins from the mit...   6 7   0.0055
HAP5 YOR358W Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding comple... CCAAT-binding transcription factor component (along with Hap2p and Hap3p) 6 10   0
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate   6 6   0.004
BBC1 YJL020C Protein possibly involved in assembly of actin patches; interacts with an actin ...   6 28   0.1267
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning, stabilize... kinesin related protein 6 38   0.0415
PRK1 YIL095W Protein serine/threonine kinase; regulates the organization and function of the ... serine/threonine protein kinase 5 18   0.0005
BIK1 YCL029C Microtubule-associated protein, component of the interface between microtubules ...   5 71 -9.5871 0
PLP1 YDR183W Protein with a possible role in folding of beta-tubulin; has similarity to phosd...   5 9   0.0037
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex, required for structural in... Ada histone acetyltransferase complex component 5 9   0.1803
CEP3 YMR168C Essential kinetochore protein, component of the CBF3 complex that binds the CDEI... Cbf3 kinetochore protein complex subunit b 5 43   0
RTT103 YDR289C Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in tran...   5 48   0.1418
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   5 26   0.0039
EAF5 YEL018W Esa1p-associated factor, subunit of the NuA4 acetyltransferase complex   5 100   0.0006
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   5 35   0
DYN3 YMR299C Dynein light intermediate chain (LIC); localizes with dynein, null mutant is def... Light intermediate chain of dynein 5 32   0.1695
MAD3 YJL013C Component of the spindle-assembly checkpoint complex, which delays the onset of ... spindle checkpoint complex subunit 5 52   0
ALT1 YLR089C Putative alanine transaminase (glutamic pyruvic transaminase)   5 11   0
BFA1 YJR053W Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell...   5 49   0.0865
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S22A (S24A) (rp50) (YS22) 5 7   0
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 4 21   0
VIK1 YPL253C Protein that forms a complex with Kar3p at the spindle pole body, possible regul...   4 16   0.1837
BNI5 YNL166C Protein involved in organization of septins at the mother-bud neck, may interact...   4 14   0
SET6 YPL165C Protein of unknown function; deletion heterozygote is sensitive to compounds tha...   4 3   0.0001
PAC1 YOR269W Protein involved in nuclear migration, part of the dynein/dynactin pathway; targ...   4 32   0.1117
CHL4 YDR254W Outer kinetochore protein required for chromosome stability, interacts with kine...   4 53   0.0003
MMM1 YLL006W Mitochondrial outer membrane protein required for normal mitochondrial morpholog... mitochondrial outer membrane protein 4 17   0.0174
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosi... tRNA:m5C-methyltransferase 4 13   0.0004
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isome... cyclophilin 40|peptidyl-prolyl cis-trans isomerase (PPIase) 4 33   0.1407
SUM1 YDR310C Transcriptional repressor required for mitotic repression of middle sporulation-...   4 139   0.1665
IML3 YBR107C Protein with a role in kinetochore function, localizes to the outer kinetochore ...   4 43   0.027

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