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SONAR Targetspace for FENDILINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 103 107
Targetspace hs pval0.130925507900680.12331838565022
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:38
Sym Orf Description Function No All Z_score hyperg
VPS41 YDR080W Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and ...   4 36   0.2065
PEP3 YLR148W Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reac... vacuolar membrane protein 4 33   0.0001
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); fu... clathrin assembly complex AP-3 adaptin component delta-like subunit 3 24   0
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two ... interacts with two t-SNARES, Sed5p and Pep12p|v-SNARE 3 39   0.0008
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p;... protein phosphatase type 2A 3 53   0.232
PEP5 YMR231W Peripheral vacuolar membrane protein required for protein trafficking and vacuol... Zn-finger protein (putative) 3 28 -14.7878 0.0009
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex; associates with core polymera... RNA polymerase II holoenzyme/mediator subunit 3 84   0.0987
YPT7 YML001W GTPase; GTP-binding protein of the rab family; required for homotypic fusion eve... GTP-binding protein|rab family 3 33   0.0613
VPS16 YPL045W Subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) compl...   3 25   0.0139
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA duri... UV endonuclease 3 44   0.0027
VMA6 YLR447C Subunit D of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase ... vacuolar ATPase V0 domain subunit d (36 kDa)|vacuolar H(+) ATPase 36 kDa subunit (D subunit of VO sector) 3 32   0.0282
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA ... DNA polymerase delta binding protein 3 73   0.2199
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex, which is involved in regulati...   3 57 -17.3881 0
VAM7 YGL212W Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-... heptad repeat motif|hydrophilic protein 3 44   0.0818
HPR1 YDR138W Subunit of THO/TREX complexes that couple transcription elongation with mitotic ...   3 54   0.001
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubi...   3 15   0.0642
PRE10 YOR362C 20S proteasome alpha-type subunit proteasome component YC1 (protease yscE subunit 1) 3 58   0
GIP3 YPL137C Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus Glc7 interacting protein 3 3 12   0.0081
NOC4 YPR144C Nucleolar protein, forms a complex with Nop14p that mediates maturation and nucl... U3 snoRNP protein 3 90   0
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 2 10   0.0043
RBG1 YAL036C Member of the DRG family of GTP-binding proteins; interacts with translating rib...   2 24   0
  YPR045C     2 15   0.0138
RTT106 YNL206C Protein with a role in regulation of Ty1 transposition   2 31   0.0092
YSH1 YLR277C Putative endonuclease, subunit of the mRNA cleavage and polyadenylation specific... cleavage factor II (CF II) component|polyadenylation factor I (PF I) 2 42   0
TID3 YIL144W Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (...   2 79   0
PUS1 YPL212C tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36... tRNA pseudouridine synthase 2 10   0
SPT5 YML010W Protein that forms a complex with Spt4p and mediates both activation and inhibit... transcription factor 2 145   0.2753
PRE2 YPR103W 20S proteasome beta-type subunit, responsible for the chymotryptic activity of t... proteasome subunit 2 63   0.1178
  YAR009C     2 9   0
DOP1 YDR141C Protein of unknown function, essential for viability, involved in establishing c...   2 16   0.1881
TOP1 YOL006C Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleavin... topoisomerase I 2 47 -5.3742 0.0252
SFL1 YOR140W Transcription repressor involved in regulation of flocculation-related genes, in... transcription factor 2 16   0
ULP1 YPL020C Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjug... Smt3-specific protease 2 27   0.1789
  YKL047W     2 5   0
  YPL009C     2 12   0
RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glu... transcriptional activator|transcriptional repressor 2 18   0
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 2 29 -22.8722 0.2288
UTP6 YDR449C Nucleolar protein, component of the small subunit (SSU) processome containing th... U3 snoRNP protein 2 75   0

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