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SONAR Targetspace for FENDILINE HYDROCHLORIDEZ-score WebGraph NB WebGraph
Targetspace hs 103 107
Targetspace hs pval0.130925507900680.12331838565022
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
ARF1 YDL192W ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of... ADP-ribosylation factor 4 126 -0.7327 0
NOT5 YPR072W Subunit of the CCR4-NOT complex, which is a global transcriptional regulator wit... NOT complex member, a global negative regulator of transcription 3 27   0.0148
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenot...   3 59   0.2392
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   3 48   0.0118
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca... P-type ATPase 3 80   0
HLJ1 YMR161W Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p pro...   3 102   0
VPS75 YNL246W Protein of unknown function involved in vacuolar protein sorting; detected in th...   2 12   0.0029
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane low affinity Fe2+ transport protein 2 7   0.1886
  At3g16720     2 11   0
  At5g58580     2 5   0
MSR1 YHR091C Mitochondrial arginyl-tRNA synthetase arginyl-tRNA synthetase 2 5   0
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 2 6   0.2679
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A), required for the posttranslational pr... vacuolar proteinase A 2 17   0.2746
AIP1 YMR092C Actin cortical patch component, interacts with the actin depolymerizing factor c... actin cortical patch component 2 12   0.0138
CAF40 YNL288W Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling...   2 13   0.069
RPL1B YGL135W N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L1B 2 30   0.0001
RRP6 YOR001W Exonuclease component of the nuclear exosome; contributes to the quality-control...   2 61 -4.1500 0.1552
RPA49 YNL248C RNA polymerase I subunit A49 RNA polymerase A 49 kDa alpha subunit 2 44 -3.3974 0.2789
TDP1 YBR223C Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3--phosphotyrosyl bonds to generate ...   2 29   0.0284
PMT1 YDL095W Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphat... dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase 2 55   0.1912
  YEL007W     2 7   0.0879
DHH1 YDL160C Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct...   2 46   0.0456
RDH54 YBR073W DNA-dependent ATPase, stimulates strand exchange by modifying the topology of do... helicase (putative)|similar to RAD54 2 19   0.2197
LEM3 YNL323W Membrane protein of the plasma membrane and ER, involved in translocation of pho... membrane glycoprotein 2 56   0
END3 YNL084C EH domain-containing protein involved in endocytosis, actin cytoskeletal organiz...   2 51   0.135
MOT2 YER068W Component of the CCR4-NOT transcription regulatory complex, which represses tran... zinc finger protein (putative) 2 72   0.1703
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediate... helicase (putative) 2 38   0.0175
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn1... required for complex glycosylation 2 5   0.0119
TOP2 YNL088W Essential type II topoisomerase, relieves torsional strain in DNA by cleaving an... topoisomerase II 2 15   0.166
UBI4 YLL039C Ubiquitin, becomes conjugated to proteins, marking them for selective degradatio... poly-ubiquitin|ubiquitin 2 25   0.2841
CHS2 YBR038W Chitin synthase II, requires activation from zymogenic form in order to catalyze... chitin synthase 2 2 2   0.0831
SPT6 YGR116W Essential protein that interacts with histones and is involved in nucleosome dis... interacts with histones, primarily histone H3, possesses nucleosome assembly activity|transcriptional regulator 2 33   0.2796
SPT5 YML010W Protein that forms a complex with Spt4p and mediates both activation and inhibit... transcription factor 2 33   0.2753
HXK1 YFR053C Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of gl... hexokinase I (PI) (also called hexokinase A) 2 6   0.2553
OCA1 YNL099C Putative protein tyrosine phosphatase, required for cell cycle arrest in respons...   1 3   0
SLA2 YNL243W Transmembrane actin-binding protein involved in membrane cytoskeleton assembly a... transmembrane protein 1 64   0.0087
RPL40B YKR094C Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a r... also encodes a ubiquitin protein|ribosomal protein L40B 1 6   0.1254
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the s... arginine specific|carbamoyl phosphate synthetase 1 5   0
FMP30 YPL103C The authentic, non-tagged protein was localized to the mitochondria   1 9   0.0235
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps1... ribosomal protein S10A 1 4   0

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