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SONAR Targetspace for FENBENDAZOLEZ-score WebGraph NB WebGraph
Targetspace hs 408 315
Targetspace hs pval00
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RBL2 YOR265W Protein involved in microtubule morphogenesis, required for protection from exce... tubulin folding cofactor A 11 30 -1.0038 NAN
CIN2 YPL241C Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; is... tubulin folding cofactor C 9 64 -52.3255 NAN
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant... GTP-binding protein 6 26   0
PNT1 YOR266W Mitochondrial inner membrane protein involved in export of proteins from the mit...   6 7   0.0055
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate   6 6   0.004
MED1 YPR070W Subunit of the RNA polymerase II mediator complex; associates with core polymera... essential for transcriptional regulation|mediator complex subunit 1 5 39   0
BBC1 YJL020C Protein possibly involved in assembly of actin patches; interacts with an actin ...   5 28   0.18
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex, required for structural in... Ada histone acetyltransferase complex component 5 9   0.1803
ALT1 YLR089C Putative alanine transaminase (glutamic pyruvic transaminase)   5 11   0
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit; nearly identical to Rps2... ribosomal protein S22A (S24A) (rp50) (YS22) 5 7   0
PLP1 YDR183W Protein with a possible role in folding of beta-tubulin; has similarity to phosd...   4 9   0.0183
UGA3 YDL170W Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent ind... zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type 4 6   0
KAR9 YPL269W Karyogamy protein required for correct positioning of the mitotic spindle and fo...   4 82   0
MMM1 YLL006W Mitochondrial outer membrane protein required for normal mitochondrial morpholog... mitochondrial outer membrane protein 4 17   0.0174
SET6 YPL165C Protein of unknown function; deletion heterozygote is sensitive to compounds tha...   4 3   0.0001
BNI5 YNL166C Protein involved in organization of septins at the mother-bud neck, may interact...   4 14   0
TUB3 YML124C Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which... alpha-tubulin 4 56 -48.7744 0
CTI6 YPL181W Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p c...   4 26   0.0013
HXK2 YGL253W Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol;... hexokinase II (PII) (also called hexokinase B) 4 27 0.0041 0.1454
  YLL007C     3 3   0.0004
  YBR108W     3 4   0
AHC2 YCR082W Protein of unknown function, putative transcriptional regulator; proposed to be ...   3 7   0.001
  YJR129C     3 2   0.0004
HAP5 YOR358W Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding comple... CCAAT-binding transcription factor component (along with Hap2p and Hap3p) 3 10   0.0137
SNT1 YCR033W Subunit of the Set3C deacetylase complex; putative DNA-binding protein   3 47   0
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates hist...   3 37   0.1873
  YGR054W     3 7   0.0004
PRK1 YIL095W Protein serine/threonine kinase; regulates the organization and function of the ... serine/threonine protein kinase 3 18   0.0257
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosi... tRNA:m5C-methyltransferase 3 13   0.0047
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation, binds alpha-tub... tubulin folding cofactor E 3 42   0
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as m... tubulin folding cofactor D 3 94   0
CEP3 YMR168C Essential kinetochore protein, component of the CBF3 complex that binds the CDEI... Cbf3 kinetochore protein complex subunit b 3 43   0.0001
THP1 YOL072W Nuclear pore-associated protein, forms a complex with Sac3p that is involved in ...   2 35   0
BUG1 YDL099W Protein of unknown function; green fluorescent protein (GFP)-fusion protein loca...   2 26   0.0002
RTT103 YDR289C Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in tran...   2 48   0.0207
ALF1 YNL148C Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP locali... tubulin folding cofactor B 2 15   0.1686
EAF3 YPR023C Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase co...   2 106   0.2551
VIK1 YPL253C Protein that forms a complex with Kar3p at the spindle pole body, possible regul...   2 16   0.2293
TUB4 YLR212C Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and... gamma tubulin 2 21   0.0145
MYO5 YMR109W One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 d... myosin I 2 25   0.1611

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