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SONAR Targetspace for 18alpha-GLYCYRRHETINIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 88 80
Targetspace hs pval0.311518324607330.53680981595092
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
RGT1 YKL038W Glucose-responsive transcription factor that regulates expression of several glu... transcriptional activator|transcriptional repressor 3 18   0
IGO1 YNL157W Hypothetical protein   2 39   0
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit; nearly identical to Rps1... ribosomal protein S10A 2 13   0
DRS2 YAL026C Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; req... P-type ATPase, potential aminophospholipid translocase 2 29 -5.1302 0.2288
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhi... vacuolar v-SNARE 2 28   0.0001
RIM15 YFL033C Glucose-repressible protein kinase involved in signal transduction during cell p... trehalose-associated protein kinase related to S. pombe cek1+ 2 34   0.0145
YPT32 YGL210W GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic p... GTPase|YPT31 homolog|ras homolog 2 26   0.1242
TPK2 YPL203W Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant c... cAMP-dependent protein kinase catalytic subunit 2 82   0.0646
APL4 YPR029C Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; ... clathrin associated protein complex large subunit|gamma-adaptin 2 21   0
CDC50 YCR094W Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p   2 5   0
DNM1 YLL001W Dynamin-related GTPase required for mitochondrial fission and the maintenance of... similar to dynamin GTPase 2 20 -5.3681 0.2663
DOT6 YER088C Protein of unknown function, involved in telomeric gene silencing and filamentat...   2 9   0.2376
CKI1 YLR133W Choline kinase, catalyzes the first step in the CDP-choline pathway phosphatidyl... choline kinase 2 11   0
FUN30 YAL019W Protein whose overexpression affects chromosome stability, potential Cdc28p subs...   2 14   0
VPH2 YKL119C Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, a... 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase 2 8   0
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation, methylates ...   2 35 1.2426 0
MDV1 YJL112W Peripheral protein of the cytosolic face of the mitochondrial outer membrane, re...   2 22   0
SPO12 YHR152W Nucleolar protein of unknown function, positive regulator of exit from mitosis; ... 20 kDa protein with negatively charged C-terminus required for function|positive regulator of exit from M-phase in mitosis and meiosis (putative) 1 60   0.2862
PSR2 YLR019W Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in ...   1 18   0
PSK2 YOL045W One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates ... PAS kinase 1 31   0.3333
  YCR079W     1 26   0.0148
  YIR007W     1 10   0
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   1 64   0.033
SIT4 YDL047W Type 2A-related serine-threonine phosphatase that functions in the G1/S transiti... similar to catalytic subunit of bovine type 2A protein phosphatase 1 79   0.0003
PRP6 YBR055C Splicing factor, component of the U4/U6-U5 snRNP complex RNA splicing factor 1 112   0
CYM1 YDR430C Lysine-specific metalloprotease of the mitochondrial intermembrane space, member... Metalloprotease 1 8   0
HIR2 YOR038C Non-essential transcriptional corepressor involved in the cell cycle-regulated t... contains nuclear targeting signal|repressor protein (putative) 1 25   0
MIG1 YGL035C Transcription factor involved in glucose repression; C2H2 zinc finger protein si... C2H2 zinc finger protein that resembles the mammalian Egr and Wilms tumour proteins 1 33   0.3795
RPC19 YNL113W RNA polymerase subunit, common to RNA polymerases I and III RNA polymerases I (A) and III (C) subunit 1 59   0
NAT4 YMR069W N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues o... N-alpha acetyltransferase 1 6   0
MCM1 YMR043W Transcription factor involved in cell-type-specific transcription and pheromone ... contains the 56 amino-acid MADS (MCM1, AG, DEFAm SRF)-box motif within its DNA binding domain, plays a central role in the formation of both repressor and activator complexes|transcription factor 1 26   0.2526
SMC6 YLR383W Protein involved in structural maintenance of chromosomes; essential subunit of ...   1 11   0.3001
CAC2 YML102W Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assemble... chromatin assembly factor-I (CAF-I) p60 subunit 1 23   0.0003
IPI3 YNL182C Protein required for cell viability; computational analysis of large-scale prote...   1 33   0
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 1 29   0
HXK1 YFR053C Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of gl... hexokinase I (PI) (also called hexokinase A) 1 16   0.3542
FHL1 YPR104C Putative transcriptional regulator with similarity to DNA-binding domain of Dros... domain similar to the fork head DNA-binding domain found in the developmental fork head protein of Drosophila melanogaster and in the HNF-3 family of hepatocyte mammalian transcription factors.|forkhead protein 1 12   0
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3... histone acetyltransferase complex component 1 14   0.2934
HST3 YOR025W Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved alo...   1 5   0.3315
COX14 YML129C Mitochondrial membrane protein, required for assembly of cytochrome c oxidase mitochondrial membrane protein 1 24   0

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