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SONAR Targetspace for 18alpha-GLYCYRRHETINIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 88 80
Targetspace hs pval0.311518324607330.53680981595092
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
GDA1 YEL042W Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-m... guanosine diphosphatase of Golgi membrane 3 33   0
FZO1 YBR179C Mitochondrial integral membrane protein involved in mitochondrial fusion and mai... Drosophila melanogaster fuzzy onions gene homolog|integral protein of the mitochondrial outer membrane; can be isolated as part of a high molecular weight complex 2 16   0.0549
TOA2 YKL058W TFIIA small subunit; involved in transcriptional activation, acts as antirepress... beta|transcription factor IIA subunit 2 11   0
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); i... adenylate cyclase regulatory protein 2 36   0.277
TPK3 YKL166C Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant c... cAMP-dependent protein kinase catalytic subunit 2 22   0.0237
TOA1 YOR194C TFIIA large subunit; involved in transcriptional activation, acts as antirepress... transcription factor IIA subunit alpha 2 9   0
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphorib... histidinol dehydrogenase 2 5   0.0195
SPT15 YER148W TATA-binding protein, general transcription factor that interacts with other fac... TFIID subunit 2 53   0.0054
BET5 YML077W Component of the TRAPP (transport protein particle) complex, which plays an esse... TRAPP 18kDa component 2 15   0.1538
NEO1 YIL048W Protein involved in the retrograde transport from the Golgi complex to the ER an... P-type ATPase 1 12   0.3796
TMA108 YIL137C Putative metalloprotease   1 15   0
TAO3 YIL129C Protein involved in cell morphogenesis and proliferation, associated with protei...   1 9   0.1537
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; requi... oligosaccharyl transferase glycoprotein complex, beta subunit 1 13   0
SPT5 YML010W Protein that forms a complex with Spt4p and mediates both activation and inhibit... transcription factor 1 33   0.2278
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; pro... ATP-binding cassette (ABC) family 1 18   0.0274
CSE4 YKL049C Centromere protein that resembles histones, required for proper kinetochore func... similar to histone H3 and to human centromere protein CENP-A 1 37   0.2318
ERG24 YNL280C C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the a... sterol C-14 reductase 1 8   0.1351
CAM1 YPL048W Translational cofactor elongation factor-1 gamma, participates in the regulation... calcium and phospholipid binding protein homologous to translation elongation factor 1-gamma (EF-1gamma) 1 3   0.3796
APL4 YPR029C Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; ... clathrin associated protein complex large subunit|gamma-adaptin 1 7   0
RPO41 YFL036W Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T... mitochondrial RNA polymerase 1 20   0.0948
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which ... 40% identical to vertebrate DAD1 protein|oligosaccharyltransferase complex 16 kDa epsilon subunit 1 4   0.3038
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   1 23   0
TRS20 YBR254C One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-...   1 5   0
PCP1 YGR101W Mitochondrial serine protease required for the processing of various mitochondri... rhomboid protease 1 4   0.0197
CWH43 YCR017C Putative sensor/transporter protein involved in cell wall biogenesis; contains 1...   1 48   0.0007
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4... zinc finger protein 1 33   0.1309
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with...   1 24   0.3794
DNF1 YER166W Non-essential P-type ATPase that is a potential aminophospholipid translocase, l... Potential aminophospholipid translocase 1 8   0.3777
CHO1 YER026C Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes t... phosphatidylserine synthase 1 14   0.117
GLK1 YCL040W Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irrever... glucokinase 1 6   0.3384
NHP6A YPR052C High-mobility group non-histone chromatin protein, functionally redundant with N... 11 kDa nonhistone chromosomal protein 1 49   0
MOB2 YFL034C-B Component of the RAM signaling network, localizes and activates the Ace2p in the... Mob1p-like protein 1 15   0
GAT1 YFL021W Transcriptional activator of genes involved in nitrogen catabolite repression, m... transcriptional activator with GATA-1-type Zn finger DNA-binding motif 1 13   0.0197
NTH1 YDR001C Neutral trehalase, degrades trehalose; required for thermotolerance and may medi... neutral trehalase 1 8 1.0929 0
SOK1 YDR006C Protein whose overexpression suppresses the growth defect of mutants lacking pro...   1 6   0.0119
CYR1 YJL005W Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinas... adenylate cyclase 1 28   0.0119
RAS1 YOR101W GTPase involved in G-protein signaling in the adenylate cyclase activating pathw... ras homolog 1 23   0.0119
STV1 YMR054W Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv... 110 kDa subunit; not in vacuole membrane|vacuolar H-ATPase 1 10   0
HST2 YPL015C Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD...   1 24   0
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two ... interacts with two t-SNARES, Sed5p and Pep12p|v-SNARE 1 11   0.1537

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