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SONAR Targetspace for LITHOCHOLIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 115 0
Targetspace hs pval0.0547368421052631
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 9 67 -2.6117 0
SWF1 YDR126W Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on a...   8 48   0
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 8 20   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   8 12   0.0002
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 56   0.0014
RPL16B YNL069C N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L16B (L21B) (rp23) (YL15) 7 14   0.0579
PKR1 YMR123W Protein of unknown function; overproduction confers resistance to Pichia farinos...   7 32   0
VPS74 YDR372C Non-essential protein of unknown function involved in vacuolar protein sorting; ...   6 47   0.1321
RUD3 YOR216C Golgi matrix protein involved in the structural organization of the cis-Golgi; i...   6 100   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   6 66 -14.2863 0
VPS17 YOR132W Subunit of the membrane-associated retromer complex essential for endosome-to-Go...   6 21   0.0534
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   6 30   0.1691
MAK10 YEL053C Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required...   6 17   0.0001
GET3 YDL100C ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins ...   5 110   0.001
VPS29 YHR012W Endosomal protein that is a subunit of the membrane-associated retromer complex ...   5 52   0.0601
VMA7 YGR020C Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPa... vacuolar ATPase V1 domain subunit F (14 kDa) 5 14   0.1616
SEC21 YNL287W Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p... PEST sequence-containing protein|non-clathrin coat protein 5 26   0.0007
MAF1 YDR005C Negative regulator of RNA polymerase III; component of several signaling pathway...   5 50   0.003
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 5 9   0
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in t... phosphatidyl-ethanolamine N-methyltransferase 5 33   0.1454
VMA22 YHR060W Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) fun...   5 17   0.1731
SWA2 YDR320C Auxilin-like protein involved in vesicular transport; clathrin-binding protein r... auxilin-like protein 5 24   0
VPS30 YPL120W Protein that forms a membrane-associated complex with Apg14p that is essential f...   5 25   0.1879
  ETG9627     5 5   0
GOS1 YHL031C v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GO...   5 56   0
ARL3 YPL051W GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to...   5 42 -9.7676 0
GAS1 YMR307W Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to th... cell surface glycoprotein 115-120 kDa 5 111 -5.3868 0
VMA10 YHR039C-A Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar ... vacuolar ATPase V1 domain subunit G (13 kDa) 5 5   0
  YDR266C     4 6   0
RIS1 YOR191W Member of the SWI/SNF family of DNA-dependent ATPases, plays a role in antagoniz... SWI2/SNF2 DNA-dependent ATPase family member (putative) 4 14   0.1813
  YOR112W     4 6   0.2085
RET1 YOR207C Second-largest subunit of RNA polymerase III, which is responsible for the trans...   4 6   0.2089
  YPL105C     4 2   0
RIM21 YNL294C Protein proposed to be involved in the response to alkaline pH; has similarity t... Unknown function 4 37   0
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); fu... clathrin assembly complex AP-3 adaptin component delta-like subunit 4 9   0
GGA2 YHR108W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 4 20   0
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   4 8   0
SEC20 YDR498C Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to... v-SNARE 4 9   0.0319
  YDR107C     4 5   0.0845

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