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SONAR Targetspace for LITHOCHOLIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 115 0
Targetspace hs pval0.0547368421052631
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:32
Sym Orf Description Function No All Z_score hyperg
BCK1 YJL095W Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinas... MEKK 30 143 -5.4474 NAN
MKK2 YPL140C Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... protein kinase 29 33   0
SLT2 YHR030C Serine/threonine MAP kinase involved in regulating the maintenance of cell wall ...   21 98 -6.5015 0
TOR2 YKL203C PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex tha...   20 89   0
MKK1 YOR231W Mitogen-activated kinase kinase involved in protein kinase C signaling pathway t... MAP kinase kinase (MEK) 20 38 -0.8594 0.0019
MYO3 YKL129C One of two type I myosins; localizes to actin cortical patches; deletion of MYO3... myosin I 19 54   0
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regul...   18 33 -19.7722 0.0942
MSB3 YNL293W GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exo... GTPase activating protein (GAP) for Ypt6 17 27   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 16 13   0
YAK1 YJL141C Serine-threonine protein kinase that is part of a glucose-sensing system involve...   16 69   0
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 14 25   0
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golg... similar to Gcs1p and Sps18p|zinc finger protein 14 48   0.0846
YIP3 YNL044W Protein localized to COPII vesicles, proposed to be involved in ER to Golgi tran...   14 43   NAN
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 14 13   0
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acy... glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase 14 20   0
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleot...   13 10 -14.2863 0
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts dow...   13 41   0
  YML037C     13 29   0
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cyto... GDP/GTP exchange factor 13 69   0
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases, appears not to be involved... monocarboxylate permease (putative) 12 11   0
UBP10 YNL186W Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may...   12 47   0
NOP2 YNL061W Probable RNA m(5)C methyltransferase, essential for processing and maturation of... 90 kDa protein homologous to a human proliferation-associated nucleolar protein, p120 12 124   0
  YDL025C     12 49   0
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   12 31   0.1278
KEM1 YGL173C Evolutionarily-conserved 5--3- exonuclease component of cytoplasmic processing (... 5--3- exonuclease 12 95 -12.3376 0.1315
NAP1 YKR048C Protein that interacts with mitotic cyclin Clb2p; required for the regulation of... nucleosome assembly protein I 12 120   0
ADH4 YGL256W Alcohol dehydrogenase type IV, dimeric enzyme demonstrated to be zinc-dependent ... alcohol dehydrogenase isoenzyme IV 12 12   0
UBP15 YMR304W Ubiquitin-specific protease that may play a role in ubiquitin precursor processi...   12 54   0
LSP1 YPL004C Integral membrane protein that along with Pil1p is a primary component of eisoso...   12 79   0
PET309 YLR067C Specific translational activator for the COX1 mRNA, also influences stability of...   12 14   0
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and ...   12 57   0
BZZ1 YHR114W SH3 domain protein implicated in the regulation of actin polymerization, able to...   11 94   0

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