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SONAR Targetspace for LITHOCHOLIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 115 0
Targetspace hs pval0.0547368421052631
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:35
Sym Orf Description Function No All Z_score hyperg
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in... clathrin associated protein complex medium subunit 11 147   0
CMP2 YML057W Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calci... calcineurin subunit A 10 46   0
FAR11 YNL127W Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway ...   10 104   0.0043
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog...   10 94   NAN
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component ... ubiquinol cytochrome C oxidoreductase subunit 6 (17 kDa) 9 60   0
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p an...   9 134   0.1295
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase and is required ... type 2A-related protein phosphatase 8 104   0
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   8 48   0
ENT5 YDR153C Protein containing an N-terminal epsin-like domain involved in clathrin recruitm...   8 112   0.0791
IRS4 YKR019C Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentr...   8 112   0.0206
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in pr... pol II transcribed genes regulator 8 80   0
EDC1 YGL222C RNA-binding protein, activates mRNA decapping directly by binding to the mRNA su...   8 28   0.0003
ASM4 YDL088C Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup17... nuclear pore complex subunit 8 94   0
PKH1 YDR490C Serine/threonine protein kinase involved in sphingolipid-mediated signaling path...   7 52   0
VAM10 YOR068C Protein involved in vacuole morphogenesis; acts at an early step of homotypic va... Required for normal tethering of vacuoles prior to fusion. 7 144   0.0267
  YDL133W     7 126   0
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   7 100   0.0011
YPT1 YFL038C Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway... GTP-binding protein|ras homolog|similar to mammalian Rab1A protein 7 91   0.0014
GDI1 YER136W GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by r... GDP dissociation inhibitor 7 37   0
MET6 YER091C Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; ... 5-methyltetrahydropteroyl triglutamate homocysteine methyltransferase|N5-methyltetrahydrofolate homocysteine methyltransferase|vitamin B12-(cobalamin)-independent methionine synthase 7 88   0.0002
MAK3 YPR051W Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for... N-acetyltransferase 7 65   0
RNH70 YGR276C 3- exoribonuclease, required for 5S and tRNA-Arg3 maturation ribonuclease H 7 79   0
CNA1 YLR433C Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calci... calcineurin subunit A 7 49   0.0116
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin, interacts with and regul... ARF-binding protein 7 72   0
GYP6 YJL044C GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved... GTPase activating protein (GAP) for Ypt6 7 107   0
KIN2 YLR096W Serine/threonine protein kinase involved in regulation of exocytosis; localizes ...   6 148   0
GEF1 YJR040W Chloride channel localized to late- or post-Golgi vesicles, involved in iron met... transport protein involved in intracellular iron metabolism (putative) 6 83   0
RAV1 YJR033C Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of th...   6 79   0.1691
USO1 YDL058W Essential protein involved in intracellular protein transport, coiled-coil prote... integrin analogue gene 6 79   0
MUD1 YBR119W U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing U1 snRNP A protein 6 109   0.0001
  YMR010W     6 72   0
RIM21 YNL294C Protein proposed to be involved in the response to alkaline pH; has similarity t... Unknown function 6 82   0
MDR1 YGR100W Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31... GTPase activating protein (GAP) for Ypt6 6 34   0
TVP15 YDR100W Integral membrane protein localized to late Golgi vesicles along with the v-SNAR... integral membrane protein 6 85   0
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein w... phosphatidylinositol 4,5-bisphosphate 5-phosphatase 6 67   0

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