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SONAR Targetspace for CHOL-11-ENIC ACIDZ-score WebGraph NB WebGraph
Targetspace hs 229 0
Targetspace hs pval0.835164835164841
XgmmL File for compound download download
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Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:39
Sym Orf Description Function No All Z_score hyperg
TIF6 YPR016C Constituent of 66S pre-ribosomal particles, has similarity to human translation ...   2 141   0
RPL24B YGR148C Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to ... ribosomal protein L24B (rp29) (YL21) (L30B) 2 22   0
NOG2 YNR053C Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus... part of a pre-60S complex 2 76   0
BRX1 YOL077C Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads t...   2 109   0.0054
YTM1 YOR272W Constituent of 66S pre-ribosomal particles, required for maturation of the large... microtubule-associated protein 2 93   0
NOC2 YOR206W Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre...   2 112   0
RPL24A YGL031C Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to ... ribosomal protein L24A (rp29) (YL21) (L30A) 2 68   0.0668
NSA2 YER126C Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit bi... ribosome biogenesis 2 52   0
URB1 YKL014C Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, as...   2 88   0
DBP3 YGL078C Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal... ATP dependent RNA helicase|dead/deah box protein CA3 2 28 -6.7526 0.0024
RSA4 YCR072C WD-repeat protein involved in ribosome biogenesis; required for maturation and e...   2 41   0
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60... Nuclear GTPase involved in Ribosome biogenesis 2 126   0
ARX1 YDR101C Protein associated with the ribosomal export complex   2 102 -1.5764 0.0657
BUD20 YLR074C Protein involved in bud-site selection; diploid mutants display a random budding...   2 74   0
KAP104 YBR017C Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous ... karyopherin beta 2 1 86   0
RPL2A YFR031C-A Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and ... ribosomal protein L2A (L5A) (rp8) (YL6) 1 126   0
IPI1 YHR085W Protein of unknown function, essential for viability, may be involved in rRNA pr...   1 26   0.0533
RPL22B YFL034C-A Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22A... ribosomal protein L22B (L1c) (rp4) (YL31) 1 4   0
RPF1 YHR088W Nucleolar protein involved in the assembly of the large ribosomal subunit; const...   1 62   0
RPL12B YDR418W Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1... ribosomal protein L12B (L15B) (YL23) 1 76   0
RPL12A YEL054C Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1... ribosomal protein L12A (L15A) (YL23) 1 47   0
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm... factor required for a late assembly step of the 60S subunit 1 56   0.0405
RPL28 YGL103W Ribosomal protein L29 of the large (60S) ribosomal subunit, has similarity to E.... ribosomal protein L28 (L29) (rp44) (YL24) 1 113   0
RPS2 YGL123W Protein component of the small (40S) subunit, essential for control of translati... ribosomal protein S2 (S4) (rp12) (YS5) 1 50   0
RPL16A YIL133C N-terminally acetylated protein component of the large (60S) ribosomal subunit, ... ribosomal protein L16A (L21A) (rp22) (YL15) 1 110   0.2721
ALB1 YJL122W Hypothetical protein   1 36   0.0745
RPL2B YIL018W Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and ... ribosomal protein L2B (L5B) (rp8) (YL6) 1 87   0
RPL27A YHR010W Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl2... ribosomal protein L27A 1 82   0
SDA1 YGR245C Highly conserved nuclear protein required for actin cytoskeleton organization an...   1 56   0.1155
RPL14B YHL001W Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1... ribosomal protein L14B 1 79   0
RPL8A YHL033C Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to R... ribosomal protein L8A (rp6) (YL5) (L4A) 1 100   0.0882
RIX1 YHR197W Essential protein involved in the processing of the ITS2 region of the rRNA locu...   1 101   0
RLI1 YDR091C Essential iron-sulfur protein required for ribosome biogenesis and translation i...   1 58   0
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the m... small nucleolar RNP protein 1 50   0
CBF5 YLR175W Component of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), pr... major low affinity 55 kDa centromere/microtubule binding protein 1 117   0.3572
NOP10 YHR072W-A Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type... H/ACA-box snoRNPs component 1 14   0
PSK2 YOL045W One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates ... PAS kinase 1 31   0.3333
NHP2 YDL208W Nuclear protein related to mammalian high mobility group (HMG) proteins, essenti... HMG-like protein 1 52   0
SNU13 YEL026W RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U... U3 snoRNP protein|U4/U6.U5 snRNP component 1 40   0

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