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SONAR Targetspace for CHOLEST-5-EN-3-ONEZ-score WebGraph NB WebGraph
Targetspace hs 193 0
Targetspace hs pval0.0372670807453421
XgmmL File for compound download download
Stats file for targetspace download download
Targetspace Analysis download download
Dataset submitted download download

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:40
Sym Orf Description Function No All Z_score hyperg
BUL1 YMR275C Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional...   2 25   0.0055
  YPR084W     2 4   0
RIM11 YMR139W Protein kinase required for signal transduction during entry into meiosis; promo...   2 10   0.0844
SNX4 YJL036W Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golg...   2 12   0.2715
RVB2 YPL235W Essential protein involved in transcription regulation; component of chromatin r... transcriptional regulator 2 20   0.0031
ELF1 YKL160W Transcription elongation factor that contains a conserved zinc finger domain; im...   1 19 -1.4388 0
CDC19 YAL038W Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoeno... pyruvate kinase 1 11   0.0659
VID30 YGL227W Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-...   1 5 -0.2678 0
NAT5 YOR253W Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-termin... N-acetyltransferase 1 4   0
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family, involved in activatin... putative mitochondrial carrier protein 1 2   0.0003
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cer... MDS1 related protein kinase 1 6   0.0294
PIH1 YHR034C Protein of unresolved function; may function in protein folding and/or rRNA proc...   1 14   0.3152
SFT2 YBL102W Non-essential tetra-spanning membrane protein found mostly in the late Golgi, ca...   1 8   0
YGK3 YOL128C Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 famil... protein kinase 1 5   0.0002
BUL2 YML111W Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular am...   1 6   0.037
YVH1 YIR026C Protein phosphatase involved in vegetative growth at low temperatures, sporulati... protein tyrosine phosphatase induced by nitrogen starvation 1 14   0.033
PGM1 YKL127W Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosp... phosphoglucomutase minor isoform 1 11   0.073
ROG1 YGL144C Protein with putative serine active lipase domain   1 6   0.0205
MDM38 YOL027C Mitochondrial inner membrane protein, required for K+/H+ exchange and for normal...   1 8   0.0001
MDM35 YKL053C-A Protein of unknown function; mutation affects mitochondrial distribution and mor...   1 6   0
MRPS8 YMR158W Mitochondrial ribosomal protein of the small subunit   1 1   0.0002
  YLR168C     1 10   0.0001
UBP2 YOR124C Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, ... ubiquitin-specific protease 1 7   0
CET1 YPL228W Beta (RNA 5--triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (... RNA 5--triphosphatase|mRNA capping enzyme beta subunit (80 kDa) 1 8   0.0002
PMD1 YER132C Protein with an N-terminal kelch-like domain, putative negative regulator of ear...   1 3   0.0205
SEC18 YBR080C ATPase required for the release of Sec17p during the -priming- step in homotypic... ATPase|NSF|protein involved in protein transport between ER and Golgi 1 33   0.2373
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3... histone acetyltransferase complex component 1 29   0.2934
SEC28 YIL076W Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein tr... epsilon-COP coatomer subunit 1 19   0
RVB1 YDR190C Essential protein involved in transcription regulation; component of chromatin r...   1 13   0.0232
RER1 YCL001W Protein involved in retention of membrane proteins, including Sec12p, in the ER;...   1 73   0.0001
  YER139C     1 18   0.0033
OXR1 YPL196W Protein of unknown function required for normal levels of resistance to oxidativ...   1 2   0.0135
  YPL105C     1 2   0.0387
  YOR112W     1 6   0.0611
INO4 YOL108C Transcription factor required for derepression of inositol-choline-regulated gen... basic helix-loop-helix (bHLH) protein 1 10   0
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in v... GTPase activating protein (GAP) 1 67 -1.1954 0
DSS4 YPR017C Nucleotide release factor functioning in the post-Golgi secretory pathway, requi... GDP dissociation factor for Sec4p 1 14   0.01
NTO1 YPR031W Component of the histone acetyltransferase complex HAT complex component 1 10   0.0936
YIP1 YGR172C Integral membrane protein required for the biogenesis of ER-derived COPII transp...   1 22   0.3799
NUP2 YLR335W Protein involved in nucleocytoplasmic transport, binds to either the nucleoplasm... nucleoporin 1 27   0

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